Hyper reflective foci (HRF) on OCT in diabetic retinopathy
1 April 2015
| Saruban Pasu
|
Retina / Uvea / Vitreous
This study investigated the presence of hyper reflective foci (HRF) in asymptomatic patients affected by type 1 or type 2 diabetes, separately, without clinically significant diabetic macular oedema and visual impairment. In total 71 eyes with non-proliferative diabetic retinopathy were...
VEGF and axial length (RVU)
1 April 2015
| Saruban Pasu
|
Retina / Uvea / Vitreous
The authors of this paper set out to examine whether the concentrations of VEGF in the vitreous were associated with refractive error and axial length in eyes without retinal disease, except of macular holes or epiretinal membranes. A vitreous sample...
Intravitreal injection related endophthalmitis
1 April 2015
| Jaya Myneni
|
Retina / Uvea / Vitreous
|
Age-related macular degeneration (AMD), endophthalmitis, intravitreal injection, post-injection complications, vascular endothelial growth factor (VEGF)
This article reviews the incidence, clinical findings, risk factors, management and visual outcomes in intravitreal injection related endophthalmitis. Incidence of this complication is reported to be in the range of 0.038% to 0.065% (1 in 2000-3000 injections). Patients present typically...
Methotrexate and mycophenolate mofetil for non-infectious uveitis
1 February 2015
| Brian Ang
|
Retina / Uvea / Vitreous
This is the first reported randomised clinical trial comparing methotrexate versus mycophenolate mofetil (MMF) for the treatment of non-infectious intermediate uveitis, posterior uveitis or panuveitis. To be eligible for recruitment, patients had to be on ≥15mg oral prednisone and demonstrated...
Timing of vitrectomy for retained lens fragments
1 February 2015
| Saruban Pasu
|
Retina / Uvea / Vitreous
The purpose of this study was to compare the results of same setting vitrectomy with delayed vitrectomy for retained lens fragments following cataract surgery. Same setting vitrectomy was defined as the patient not leaving the operating table following cataract surgery....
Medical management and diabetic retinopathy progression
1 February 2015
| Brian Ang
|
Retina / Uvea / Vitreous
The ACCORD Eye Study was designed to evaluate the benefit of intensive glycaemic control (HbA1c <6.0% vs 7.0-7.9%), intensive systolic blood pressure control (<120mmHg vs. <140mmHg), and combined fenofibrate and simvastatin therapy in the development and progression of diabetic retinopathy....
Prognostic information for PRP-naive patients
1 February 2015
| Saruban Pasu
|
Retina / Uvea / Vitreous
The Diabetic Retinopathy Study group demonstrated that pan retinal laser photocoagulation (PRP) reduces severe vision loss by up to 50% in cases of proliferative diabetic retinopathy (PDR). The authors of this current study aimed to provide information for laser naive...
Comparison of ganglion cell thinning in glaucoma vs. macular hole repair
1 December 2014
| Khadijah Basheer
|
Retina / Uvea / Vitreous
|
Ganglion cell complex, PhNR, glaucoma, macular hole, photopic negative response
This prospective study compared the changes in the photopic negative response of the focal macular electroretinogram (fmERG) caused by retinal ganglion cell complex (GCC) thinning at the macula between patients with open angle glaucoma (OAG) and 12 months after successful...
Choroidal thickness in ocular sarcoidosis by OCT measurement
1 December 2014
| Nikolaos D Georgakarakos
|
Retina / Uvea / Vitreous
|
Choroidal thickness, enhanced depth imaging optical coherence tomograph, quiescent phase, sarcoidosis, uveitis
This is the first study to evaluate the choroidal thickness in patients with ocular sarcoidosis during the quiescent phase using enhanced depth imaging optical coherence tomography (EDI-OCT) and comparing with normal subjects. Ocular sarcoidosis may affect the choroidal circulation (occlusive...
Diagnostic procedures in vitreoretinal lymphoma.
1 December 2014
| Nikolaos D Georgakarakos
|
Retina / Uvea / Vitreous
|
Biopsy, diagnosis, masquerade, vitrectomy, vitreoretinal lymphoma
This paper presented a retrospective review of medical records of HIV negative immunocompetent patients diagnosed with vitreoretinal lymphoma between 1994 and 2012. The aim of the paper was to evaluate the type and number of diagnostic interventions required to confirm...
Fluorescein angiography and OCT in myopic CNV
1 December 2014
| Bheemanagouda Patil
|
Retina / Uvea / Vitreous
Fluorescein angiography (FA) and spectral-domain optical coherence tomography (OCT) are the most common examinations used in the management of anti-VEGF therapy in choroidal neovascularisation (CNV). In comparison to FA, OCT provides a noninvasive evaluation of the macula. Myopic CNV are...
Detection of antiranibizumab antibodies in exudative AMD
1 December 2014
| Sofia Rokerya
|
Retina / Uvea / Vitreous
In this study the authors aimed to detect immune response to ranibizumab treatment in wet age-related macular degeneration (AMD). An ELISA was employed to quantify the anti-ranibizumab titre which was compared against the control anti-abciximab titre. Titres of anti-ranibizumab antibodies...
