Akimba mice, a model of human diabetic retinopathy
1 October 2014
| Graham Wallace
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Retina / Uvea / Vitreous
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Akimba, BRB, PLVAP, blood-retinal barrier, diabetic macular edema, diabetic retinopathy, mouse models, retina
Diabetic retinopathy (DR) is a major complication of diabetes and a growing problem as the systemic disease becomes more prevalent. DR develops insidiously from an asymptomatic form through to vascular damage that leads to oedema and breakdown of the blood-retinal...
B-scan ultrasonography
1 October 2014
| Nana Theodorou
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Retina / Uvea / Vitreous
B-scan ultrasonography is commonly employed for the diagnosis and follow-up of ocular trauma. This retrospective study looked at the accuracy and predictive ability of B-scan ultrasonography following open globe repair. Of the 965 patients identified with open globe injuries at...
Early surgery for epiretinal membrane
1 October 2014
| Nana Theodorou
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Retina / Uvea / Vitreous
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epiretinal membrane, combined phakovitrectomy, OCT
This was a retrospective case review study in 120 consecutive patients with idiopathic epiretinal membrane. The average patient age was 72 years with a mean follow-up of 6.5 months. Inclusion criteria consisted of symptomatic patients with visual acuity of 1.0...
Resolution of mid-peripheral schisis in x-linked retinoschisis with the use of dorzolamide
1 October 2014
| Huw Edward Oliphant
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Retina / Uvea / Vitreous
X-linked retinoschisis (XLRS) is an early onset hereditary retinal dystrophy. It is caused by mutations of the RS1 gene. Common manifestations of XLRS are schitic lesions at the macula, as well as infero-temporal schisis. Carbonic anhydrase inhibitors have previously been...
Effect of laser wavelength on delivering effective burns through opaque lens using pattern scan laser
1 October 2014
| Bheemanagouda Patil
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Retina / Uvea / Vitreous
Panretinal photocoagulation (PRP) has been used in the treatment of various retinal disorders for many decades. Conventional single-spot lasers take quite some time to do with significantly higher pain, anxiety and photophobia when compared to the pattern scan laser (PSL)....
Progression of myopic maculopathy after treatment
1 October 2014
| Sofia Rokerya
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Retina / Uvea / Vitreous
The authors report on a retrospective study carried out to evaluate long-term progression of myopic maculopathy and functional outcome in eyes treated for myopic choroidal neovascularisation (CNV) and in eyes without CNV. Fifty-four myopic eyes of 30 patients were included...
Visual fields and OCT in hydroxychloroquine retinopathy
1 October 2014
| Brian Ang
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Retina / Uvea / Vitreous
It has been recommended that patients on hydroxychloroquine be monitored regularly for retinopathy. However, there has not been an agreement as to the best screening test for hydroxychloroquine toxicity, which may include visual fields (VF), fundus autofluorescence, spectral domain optical...
Optical coherence tomography in patients exposed to vigabatrin
1 August 2014
| Nana Theodorou
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Retina / Uvea / Vitreous
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anti-epileptic drug, drug toxicity, full-field electroretinography, optical coherence tomography, vigabatrin, visual field defect
Vigabatrin is used to treat epilepsy and can lead to increased levels of gamma-aminobutyric acid (GABA) in the brain and in the retina leading to binasal visual field defects. Although not the first line of treatment for adults it is...
Gender variations in retinopathy
1 August 2014
| Nana Theodorou
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Retina / Uvea / Vitreous
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blood pressure, cardiovascular disease, epidemiology, hypertension, microalbuminuria, prevalence, retinopathy, risk factors, urinary albumin excretion
The Tromso Eye Study is a substudy of the Tromso Study; a population based longitudinal study based in Norway. The extensive 5869 participants had no diabetes and were aged between 30-87 years. Retinal images from both eyes were taken using...
Epiretinal membranes in uveitic macular oedema
1 August 2014
| Efrosini Papagiannuli
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Retina / Uvea / Vitreous
Epiretinal membrane (ERM) formation in uveitic macular oedema is a fairly common structural complication of the retina. The authors describe a retrospective case series of 104 eyes of 77 patients with uveitic macular oedema from a tertiary centre. The treatment...
Reduced blood flow and age-related macular degeneration
1 August 2014
| Khadijah Basheer
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Retina / Uvea / Vitreous
This was a prospective cross-sectional study assessing changes in blood flow velocity in patients with age-related macular degeneration (AMD) using a retinal function imager. Sixty eyes with wet AMD were compared to 53 control eyes and the average blood flow...
Complement factor B polymorphism and the phenotype of early age-related macular degeneration
1 August 2014
| Huw Edward Oliphant
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Retina / Uvea / Vitreous
The relationship between complement factor H (CFH) and age-related macular degeneration (AMD) is very well known, but other genetic polymorphisms relating to AMD are more poorly understood. This study was designed to investigate the relationship between complement factor B (CFB)...
