Journal Reviews
Efficacy of intravitreal dexamethasone implant in patients with persistent macular oedema
Chronic cystoid macular oedema (CME) can develop secondary to various pathologies such as diabetic maculopathy, retinal vein occlusion and uveitis. It can cause significant visual impairment and macular damage. The therapeutic effect of corticosteroids in CME is through one or...
Uveitis in HIV infected persons
Before the advent of highly active antiretroviral therapy (HAART), uveitis, in particular cytomegalovirus (CMV) retinitis, was the most common cause of visual loss in patients with AIDS. HAART has altered the cause of ocular disease in HIV infected individuals by...
Ranibizumab versus laser in diabetic macular oedema (LUCIDATE study)
The aim of this study was to compare the functional and structural effects of Ranibizumab versus macular laser treatment in patients with diabetic macular oedema. It was a single centre, prospective, randomised, single masked clinical trial spanning a 48 week...
The choroid in pregnancy
During pregnancy there can be different types of ocular changes including a decrease in corneal sensitivity, increase in central corneal thickness and curvature, decrease in intraocular pressure, central serous chorioretinopathy and ocular blood flow. Advances in ophthalmic imaging devices has...
MicroRNA mediate retinoblastoma signal transduction
MicroRNAs (miR) are small non-coding single-stranded RNA molecules, normally 22 nucleotides long. There is a large family of miR that control protein expression by binding to mRNAs, leading to their degradation. One important role of miR is in tumours where...
Akimba mice, a model of human diabetic retinopathy
Diabetic retinopathy (DR) is a major complication of diabetes and a growing problem as the systemic disease becomes more prevalent. DR develops insidiously from an asymptomatic form through to vascular damage that leads to oedema and breakdown of the blood-retinal...
B-scan ultrasonography
B-scan ultrasonography is commonly employed for the diagnosis and follow-up of ocular trauma. This retrospective study looked at the accuracy and predictive ability of B-scan ultrasonography following open globe repair. Of the 965 patients identified with open globe injuries at...
Early surgery for epiretinal membrane
This was a retrospective case review study in 120 consecutive patients with idiopathic epiretinal membrane. The average patient age was 72 years with a mean follow-up of 6.5 months. Inclusion criteria consisted of symptomatic patients with visual acuity of 1.0...
Resolution of mid-peripheral schisis in x-linked retinoschisis with the use of dorzolamide
X-linked retinoschisis (XLRS) is an early onset hereditary retinal dystrophy. It is caused by mutations of the RS1 gene. Common manifestations of XLRS are schitic lesions at the macula, as well as infero-temporal schisis. Carbonic anhydrase inhibitors have previously been...
Effect of laser wavelength on delivering effective burns through opaque lens using pattern scan laser
Panretinal photocoagulation (PRP) has been used in the treatment of various retinal disorders for many decades. Conventional single-spot lasers take quite some time to do with significantly higher pain, anxiety and photophobia when compared to the pattern scan laser (PSL)....
Progression of myopic maculopathy after treatment
The authors report on a retrospective study carried out to evaluate long-term progression of myopic maculopathy and functional outcome in eyes treated for myopic choroidal neovascularisation (CNV) and in eyes without CNV. Fifty-four myopic eyes of 30 patients were included...
Visual fields and OCT in hydroxychloroquine retinopathy
It has been recommended that patients on hydroxychloroquine be monitored regularly for retinopathy. However, there has not been an agreement as to the best screening test for hydroxychloroquine toxicity, which may include visual fields (VF), fundus autofluorescence, spectral domain optical...
