Journal Reviews
Treatment options for septic cavernous sinus thrombosis
Septic cavernous sinus thrombosis is a rare but serious complication of infection of the cavernous sinuses. Potential therapies include antibiotics, corticosteroids and anticoagulation, as well as surgical intervention for source control of the infection. The authors report that there is...
Resolution of idiopathic intracranial hypertension (IIH): case series
The authors report the findings from 14 patients following treatment for idiopathic intracranial hypertension (IIH). All 14 patients experienced an immediate and sustained resolution of the IIH in the setting of prolonged cerebrospinal fluid (CSF) drainage at a rate greater...
Histopathological changes in rabbit retinitis pigmentosa
The authors report the histopathological changes of retinal ganglion cells (RGCs), optic disc and optic nerve in rabbit with advanced retinitis pigmentosa (RP). RP was recreated in rabbits by using bacterial artificial chromosome transgenesis, with the purpose of increasing understanding...
Systematic review on vergence neural pathways
A full systematic review of the literature was carried out by the authors, to identify literature available on vergence neural pathways and associated disorders. The review included articles related to vergence neural pathways, along with articles that discussed the anatomy,...
Online tool for converting finger counting acuity into Snellen equivalent
The authors describe an online tool which has the purpose of converting count finger measurements of visual acuity into Snellen equivalents. The purpose of this is to allow the re-interpretation of retrospectively collected data that provide visual acuity in this...
Advanced vestibular Schwannoma case report
Vestibular Schwannoma is a benign, slow growing tumour which usually presents with unilateral hearing loss. It causes symptoms and findings on ophthalmic examination when the diagnosis is delayed. Ophthalmic findings may be related to the effect of the expanding mass...
Bilateral internuclear ophthalmoplegia
Bilateral internuclear ophthalmoplegia (INO) has been linked with various pathological conditions of the central nervous system such as multiple sclerosis, stroke, tumours and brainstem inflammatory processes. This unusual case report describes a case of a 45-year-old female patient presenting with...
Bitemporal hemianopsia as a result of ethambutol toxicity
The authors present six cases of visual loss in patients treated with ethambutol for mycobacterium avium complex, including four patients with bitemporal hemianopsia. Two additional patients were undergoing glaucoma monitoring and developed visual field defects with ethambutol treatment, which recovered...
Case report of Leber hereditary optic neuropathy (LHON)
This case report presents a 74-year-old male patient who developed LHON, with a previous diagnosis of bilateral macular holes. LHON occurs predominantly in healthy young men and onset in older age ranges increases the likelihood that the patient will have...
Review of non-arteritic anterior ischaemic optic neuropathy
This article reviews the risk factors, clinical presentation and therapies that have been investigated for non-arteritic anterior ischaemic optic neuropathy (NAAION). Additionally, it provides an update from recent rodent and primate models, offering a new insight into the pathophysiology of...
Leber’s hereditary optic neuropathy: from lab to clinic
Leber’s hereditary optic neuropathy (LHON) was the first clinically described mitochondrial disorder (1871). This article reviews the pathophysiology and clinical features of LHON with a focus on translational research. G11778A is currently the most common mutation worldwide and is associated...
Comparison of treatment for hemianopia following stroke
The authors report the screening process and recruitment figures for a randomised controlled trial comparing interventions for post stroke homonymous hemianopia. Interventions included Fresnel prisms, visual search training and standard care (information only). Primary outcome measure was the change in...
