Journal Reviews
Aquaporin-4 antibody testing in isolate optic neuritis
The authors present a retrospective case review of first presentation isolated cases of optic neuritis tested for aquaporin-4 antibody across two centres over a nine-year period. Exclusion criteria included known diagnosis or other manifestations of neuromyelitis optica spectrum disorder. Two...
Case reports of neuro-visual consequences of mild COVID-19 in children
Neuro-visual involvement has been reported in numerous patients with severe SARS-CoV-2 disease, mainly among adult patients. In children, such involvement has been reported in rare cases, often in those presenting with severe forms of COVID-19. The aim of this work...
Using a tumour registry to investigate optic nerve gliomas
This study is a retrospective comparative analysis. Patients with optic nerve glioma and pilocytic astrocytoma were identified through the Surveillance, Epidemiology and End Results (SEER) cancer registry covering a 42-year period using standardised codes. The following data was extracted: basic...
Assessing possibility of deferring lumbar puncture in mild idiopathic intracranial hypertension
This was a retrospective review of patients consecutively presenting with idiopathic intracranial hypertension (IIH) to a tertiary neuro-ophthalmology clinic without a lumbar puncture (LP) over an eight-year period. Inclusion criteria included true optic disc oedema, retinal nerve layer thickness ≤300µm,...
Higher risk of poor functional outcome in the presence of visual deficits post-stroke
The authors present a retrospective case review with the aim of reporting the disability outcomes of individuals 90-days post stroke with and without visual deficits. The Houston Methodist Hospital Outcomes-based Prospective Endpoints in Stroke (HOPES) Registry was used as the...
Narrative review of idiopathic intracranial hypertension in children / adolescents
Idiopathic intracranial hypertension (IIH) affects both children and adults. Whilst the majority of IIH is mainly seen amongst adults, it also affects children. There are currently no clinical trials in IIH for those who are adolescents or children. The aims...
Agreeing terminology for non-classic visual field abnormalities
The authors present a prospective survey of neuro-ophthalmologists. The survey comprised of 10 visual fields. The selection of visual fields for the survey aimed for variety and excluded classic neuro-ophthalmology visual field defects, e.g. hemianopia, nasal step. The survey was...
Rare presentation of giant cell arteritis in Chinese subjects
Only a few case reports of biopsy-proven GCA (BpGCA)-associated vision loss in Chinese subjects have been published. This paper presents three elderly Chinese subjects with BpGCA who presented with vision loss. A search of the literature was also conducted to...
Single case report of horizontal gaze paresis due to medial pontine haemorrhage
The authors report a single case (80-year-old female) of bilateral horizontal conjugate gaze palsy due to a dorsal median pontine haemorrhage. The patient presented with skew deviation, bilateral horizontal conjugate gaze palsy, vertical gaze palsy, ipsilateral lower motor neuron facial...
Predicting ischemic lesion location using perimetry
The authors present a retrospective records review, using the search terms homonymous hemianopia, visual field loss and MRI. Only posterior circulation artery territory ischemic strokes were included. Demographics, stroke details and initial and follow-up with 24-2 SITA Standard perimetry results...
Exploring the potential of neurodegenerative disease screening within age-related eye disease research
The authors recruited healthy controls aged between 60 and 75-years-old, previously enrolled into a registry as patients following cataract surgery without age-related macular degeneration (AMD). Exclusion criteria included dense cataract, retinal disease, ocular inflammatory disease, moderate glaucoma, optic neuropathy, cancer,...
Use of international interocular difference thresholds for optic neuritis diagnosis in clinical practice
Multiple sclerosis (MS) is the most common non-traumatic cause of disability in young people, and visual symptoms can be the initial manifestation in up to 20% of cases. Retinal examination can be helpful in making the correct diagnosis. The latest...
