Incidence, microbiological profile and in vitro antimicrobial susceptibility of IK
This is a retrospective single centre study of all patients (with corneal scraping) including their demographic factors, microbiological profiles, and in vitro antibiotic susceptibility of infectious keratitis (IK), studied between 2007 and 2019. The incidence of IK was 34.7/100,000 people...
Effect of long-term RGP-CL wear on keratoconus progression
This is a retrospective study between April and December 2017, of 22 rigid gas-permeable contact lens (RGP-CL) patients (31 eyes) and 15 non-CL patients (20 eyes) who fulfilled the criteria of: 1) >3 years follow-up and 2) Scheimpflug-based corneal imaging...
Effect of long-term scleral contact lenses on corneal topography, tear film and impression cytology in keratoconus
This study of 16 keratoconus patients aimed to investigate the impact of long-term scleral contact lens (ScCL) wear on corneal curvature, corneal thickness, tear film function and ocular surface in patients with keratoconus. Corneal topography, tear osmolarity test, Schirmer 1...
Acanthamoeba keratitis
This is a retrospective case series on medical records and corneal photographs of 40 eyes of 35 patients with acanthamoeba keratitis (AK, culture positive or with histopathological diagnosis). The mean age of onset was 30 ±15 years (younger in females)....
Cell injection therapy for endothelial failure
This is a prospective observational study involving 11 eyes of 11 patients with pseudophakic endothelial failure who underwent human corneal endothelial cell culture (hCEC) injection therapy for endothelial failure. This study aimed to evaluate the long-term five-year postoperative data for...
Long-term effect of YAG LPI on corneal endothelium in PACS
This is a single-centre randomised controlled trial of 875 patients with bilateral primary angle closure suspect (PACS) who received YAG laser iridotomy (LPI) prophylactic treatment in one eye randomly and the fellow eye served as control over 72 months. Central...
Proning and ocular injury
This systemic review and meta-analysis investigated the incidence and type of ocular injuries reported in adult critical care from both prone and supine patients between January 1990 and July 2020. They reviewed 11 randomised controlled trials. In three trials, 28...
Presentation of conjunctival intraepithelial neoplasia
Ocular surface squamous neoplasia is the umbrella term for malignancies of the conjunctiva and within the spectrum lies conjunctival intraepithelial neoplasia (CIN) – a non-invasive malignancy. CIN has been implicated with ageing, smoking and ultraviolet light exposure. The typical manifestation...
A robotic armrest for ophthalmic surgery
Robot-assisted ophthalmic surgery has been the focus of intense interest in recent years. In this study, the authors tested the potential utility of a robotic armrest in ophthalmic surgery. The iArmS device consists of a forearm rest attached to a...
Light tolerance in infectious keratitis
The authors presented the findings of a study that aimed to identify the maximum irradiance (power received by a surface per unit area) that can be tolerated by photophobic patients with infectious keratitis (IK). They recruited 30 patients (14 women...
Characteristics of limbal lymphatic vasculature on confocal microscopy
This ex vivo study aims to describe the morphological characteristics of the human limbal lymphatic vasculature using confocal microscopy and immunofluorescence. Twelve corneal specimens are obtained from human donor eyes. These corneal buttons are not suitable for transplantation due to...
Review of pathogenesis of Acanthamoeba keratitis
In this review, the author summarised the current microbiomic and immunological evidence related to the pathogenesis of Acanthamoeba keratitis (AK). AK has been described for almost 50 years, but the exact biology of the disease remains perplexing. Acanthamoeba spp. are...
