Journal Reviews
Multiple sclerosis and the ocular manifestations
This population study retrospectively identified patients with multiple sclerosis (MS) over a 14-year period. The aim of the study was to report the frequency and severity of ocular conditions associated with MS. Cases were identified from the Rochester Epidemiology Project....
Improvement of visual acuity with dichoptic training for amblyopia
This study evaluated the effectiveness of dichoptic amblyopia treatment using the Bynocs AmblyGo programme in reversing various types of amblyopia in a retrospective cohort. At recruitment, all patients had demonstration of the treatment. Patients continued treatment at home via internet-connected...
Ground control to optic nerve – the space oddity to be studied
The authors explore the clinical entity that is known as Spaceflight Associated Neuro-ocular Syndrome (SANS). Its clinical characteristics include optic disc oedema, hyperopic refractive shifts, globe flattening, and chorioretinal folds, may pose a health risk for future space exploration. Understanding...
Covid-19 ophthalmopathy
Ocular involvement is not uncommon in patients with Covid-19. However, the incidence of Covid-19 ophthalmopathy is unclear. The authors present a prospective case series including 2445 consecutive cases presenting at a neuro-ophthalmology clinic during the last resurgence of SARS-CoV-2 infection....
How does teprotumumab impact on ocular misalignment in thyroid eye disease?
A retrospective case review was conducted with the aim of exploring the effect of teprotumumab on objective diplopia. Adults diagnosed with thyroid eye disease, presenting with diplopia and receiving a standard six-month treatment with teprotumumab at a single centre were...
Primary visual pathway changes in individuals with chronic mild traumatic brain injury
Patients with mild traumatic brain injury (mTBI) often self-report vision disturbance despite showing no reduction of visual acuity or fundus examination abnormality. This prospective, observational, cross-sectional study aimed to determine if using a sweeping array of investigations can help diagnose...
Avoiding prominent facial features during perimetry
The authors present a case series including six healthy participants prospectively recruited. All participants had no ocular pathology. The assessment included identification of their dominant eye for use in testing. A 60-4 SITA standard visual field assessment was completed in...
Current literature evidence for fulminant idiopathic intracranial hypertension
Fulminant idiopathic intracranial hypertension (IIH) is a rapid vision-degrading presentation of IIH with limited published studies. This narrative review aims to collate current knowledge around fulminant IIH presentation and visual outcomes. Search terms included IIH, benign intracranial hypertension, or pseudo-tumour...
How common is empty sella in neuro-ophthalmology patients not suspected of raised intracranial pressure
The study aimed to assess how common the presence of empty / partially empty sella is amongst neuro-ophthalmology patients undergoing magnetic resonance imaging (MRI) excluding for papilledema and raised intracranial pressure (ICP). The study retrospectively reviewed case records of consecutive...
Predicting visual prognosis of patients with methanol poisoning
Symptoms of methanol poisoning often occur 12–24 hours after oral consumption, and visual symptoms are seen in approximately 50% of cases. This study aims to investigate the role of optic nerve diffusion status on cranio-orbital magnetic resonance imaging (MRI) in...
Does modern radiological imaging detect lesions associated with internuclear ophthalmoplegia?
The authors present a retrospective case review including all patients with a diagnosis of internuclear ophthalmoplegia (INO) presenting to two tertiary neuro-ophthalmology centres over a five-year period. The aim of the study was to assess the sensitivity of modern radiological...
What are the characteristics of patients reporting diplopia in giant cell arteritis?
The authors present a retrospective study of individuals diagnosed with giant cell arteritis (GCA) consecutively over a six-year period at a single tertiary ophthalmic centre. The characteristics of binocular diplopia prior to GCA diagnosis was collected from medical records and...
