A prospective trial of adjuvant therapy for high-risk melanoma
Patients diagnosed with iris, ciliary body or choroidal melanoma of high-risk tumour cytogenetics (monosomy 3>/= 20% of cells), were treated with adjuvant low-dose dacarbacine (DTIC) and interferon –alpha-2b (IFNA-2b), following primary treatment (enucleation, brachytherapy or resection). DTIC was given intravenously...
Laissez-faire approach for medial canthus tumours
This is a retrospective comparative case series of patients who underwent reconstruction of a medial canthal defect using laissez-faire approach (LFS), or a full-thickness skin graft (FTSG). The surgical options were discussed with the patient and the treatment decision was...
Efficacy of browpexy with blepharoplasty
1 October 2017
| Jaya Myneni
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EYE - Pathology, EYE - Oncology
|
Blepharoplasty, brow lift, brow ptosis, browpexy
This is a retrospective case series evaluating the efficacy of and comparing the surgical results between internal (IB) and external browpexy (EB) surgery in lifting central and lateral brow. Patients who underwent blepharoplasty without brow lift were used as a...
Outcomes of punch punctoplasty with Kelly punch
The authors report a retrospective case series study, over an eight-year period between January 2008 to January 2016 evaluating the long-term outcomes of punch punctoplasty by Kelly punch as a primary treatment for punctal stenosis; 101 punch punctoplasties from 50...
Bioengineered human tissue
1 August 2017
| James Hsuan
|
EYE - Pathology, EYE - Oncology
|
ocular, oculoplastic, reconstructive, bioengineering, reconstruction, oculoplastics, orbit
This is a literature review of the current status of tissue engineering related to ocular and oculoplastic reconstructive surgery. The authors describe the process of bioengineering for tissue reconstruction. The aim is to reproduce functional tissue by the use of...
AlloDerm for correction of lower lid retraction
1 August 2017
| James Hsuan
|
EYE - Pathology, EYE - Oncology
|
Graves’ orbitopathy, orbital decompression, acellular human dermis, Oculoplastics, orbit
This is a retrospective review of 95 eyes of 54 patients undergoing orbital decompression for Graves’ orbitopathy. All patients had a swinging eyelid approach across the whole of the lower lid. Thirty-six eyes also had insertion of a 0.3mm thick...
High dose (2.5mg) bevacizumab for postradiation cystoid macular oedema
1 April 2017
| Yamini Krishna
|
EYE - Pathology, EYE - Oncology
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Anti-VEGF, Cystoid macular edema, Melanoma, Radiation damage, Radiotherapy, Tumor
The authors present a retrospective, interventional case series investigating the efficacy of high dose (2.5mg/0.1ml) intravitreal bevacizumab in the treatment of persistent postradiation (Iodine-125 plaque brachytherapy for uveal melanoma) cystoid macular oedema (CME). Persistent CME was defined as increased or...
Atopic keratoconjunctivitis (AKC) and ocular surface squamous neoplasia (OSSN)
1 April 2017
| Yamini Krishna
|
EYE - Pathology, EYE - Oncology
|
Atopia, Inflammation, Masquerade, Neoplasia, Ocular surface
The authors present two cases of invasive OSSN in patients with severe AKC. Case 1 was a 73-year-old male with severe AKC and atopic eczema who developed a suspicious papillary-like limbal lesion in the left eye. He had an excisional...
Suspected vitreous seeding of uveal melanoma
This is a retrospective non-randomised study of 23 patients with consecutive uveal melanoma who underwent diagnostic vitrectomy between the period of January 2000 and November 2013. The reason for vitrectomy was suspected dissemination of tumour cells inside the eye. The...
Imiquimod for lentigo maligna
This is a retrospective review of 12 patients with periocular lentigo maligna treated with topical 5% imiquimod cream. In six patients it was the only treatment, and in the other six it was used following partial excision, cryotherapy or both....
Serology testing in periocular inflammatory disease
This is a review article of serological tests in thyroid eye disease, IgG4-related disease and myasthenia gravis. The authors provide an overview of the current serology with a brief description of how they relate to the pathogenesis of each condition....
Squamous metaplasia of conjunctival epithelial cells with soft contact lens wear versus non-lens wearers
Conjunctiva is composed of non-squamous epithelial cells interspersed with goblet cells, which is a secretory epithelium. Squamous metaplasia is a transformation to non-secretory epithelium, ‘keratinised’ and enlargement of the conjunctival non-goblet cells and relatively shrunken nuclei are seen on impression...
