High rate of conversion from ocular hypertension (OH) to glaucoma (UG) in subjects with uveitis
5 June 2023
| Jonathan Chan
|
EYE - Glaucoma
|
glaucoma, infection, inflammation, treatment medical, treatment surgery
This is a retrospective study from Auckland over a 10-year period including 188 eyes of 139 subjects with either OH or UG and were included for analysis with a mean follow-up of 9.9 years. The most common uveitis causes were...
High rate of conversion from ocular hypertension to glaucoma in subjects with uveitis
3 April 2023
| Jonathan Chan
|
EYE - Glaucoma
|
glaucoma, infection, inflammation, treatment medical, treatment surgery
This is a retrospective study from Auckland over a 10-year period. A total of 188 eyes of 139 subjects with either ocular hypertension (OH) or uveitic glaucoma (UG) were included for analysis with a mean follow up of 9.9 years....
Inflammation and microvascular changes in diabetic retinopathy
1 February 2022
| Kurt Spiteri Cornish
|
EYE - Vitreo-Retinal
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Aqueous flare, diabetes mellitus, diabetic retinal neuropathy, diabetic retinopathy, intraocular inflammation, neuroinflammation
Studies have shown that neurodegeneration and inflammation in the retina start early in diabetic retinopathy (DR) and can be present before the latter is clinically evident. The aim of this retrospective review of 99 diabetic patients was to evaluate retinal...
A novel way to distinguish between types of anterior ischaemic optic neuropathy
7 April 2021
| Claire Howard
|
EYE - Neuro-ophthalmology
|
Anterior ischaemic optic neuropathy, inflammation, monocyte to high-density lipoprotein ratio
The authors evaluate the monocyte to high-density lipoprotein (HDL) ratio (MHR) in patients with arteritic and non arteritic anterior ischaemic optic neuropathy (A-AION / NA-AION). A distinction between the two types of AION is essential to begin appropriate treatment, which...
Topical nonsteroidal ant-inflammatory drugs (NSAIDs) in patients undergoing cataract surgery
4 February 2021
| Kurt Spiteri Cornish
|
EYE - Cataract, EYE - Refractive
|
Postoperative inflammation, cataract surgery, diclofenac, laser flare meter, nepafenac
Inflammation is a major risk factor for the development of cystoid macular oedema (CMO) after cataract surgery, leading to breakdown of the blood-retina barrier. There is a correlation between severity of CMO and level of postoperative inflammation. Laser flare meter...
IOP in children with uveitis
1 August 2019
| Jonathan Chan
|
Retina / Uvea / Vitreous
|
child health (paediatrics), glaucoma, inflammation, uveitis
This is a retrospective study of paediatric uveitis (<16-years-old) between July 2002 to June 2016 of a total of 320 children from a single centre: 17.2 % (55/320 patients) developed raised IOP requiring therapy; 11.5% of eyes required glaucoma surgery...
Diclofenac versus Bromfenac after cataract surgery
1 April 2019
| Kurt Spiteri Cornish
|
EYE - Cataract, EYE - Refractive
|
Non-steroidal anti-inflammatory drugs, bromfenac, cataract surgery, diclofenac, intraocular inflammation
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used after cataract surgery to reduce inflammation and cystoid macular oedema (CMO). Diclofenac 0.1% is used three to five times daily for 28 days and Bromfenac 0.09% twice daily for 14 days postoperatively. The...
Features of Behcet’s disease
1 April 2019
| Jonathan Chan
|
EYE - Neuro-ophthalmology
|
imaging, immunology, inflammation, optic erve
This is a retrospective single centre study from Paris, France, between the periods of 1986 to 2015. Twenty-nine out of 217 (13.3%) neuro-Behcet’s disease (NBD) patients presented with neuro-ophthalmic manifestations (55% of men and mean age of 28 years). Sixteen...
Meta-analysis of HLA B27 associated acute anterior uveitis
1 August 2018
| Mrinal Rana
|
Retina / Uvea / Vitreous
|
Ankylosing spondylitis, fibrin, glaucoma, hypopion, ocular inflammation
A literature-based meta-analysis was carried out to look at the various clinical features associated with HLA- B27 acute anterior uveitis (AAU). After an extensive search of literature for HLA B27 uveitis was conducted, 735 results were obtained. Twenty-nine articles were...
Trochleitis features
1 April 2018
| Fiona Rowe (Prof)
|
Paediatric Ophthalmology / Strabismus
|
Brown syndrome, headache, primary trochlear headache, trochlear inflammation, trochleitis
The authors evaluate the epidemiology, clinical signs, treatment and outcomes of trochleitis in a retrospective review of 59 cases. Estimated prevalence was 12 per 100,000. Eighty-six percent were female and mean age was 43±18 years. All but one case was...
MISS vs. fornix approach
1 December 2016
| Fiona Rowe (Prof)
|
Paediatric Ophthalmology / Strabismus
|
Fornix approach, horizontal strabismus, inflammation, minimally invasive strabismus surgery, surgical time
The objectives of this study were to compare minimally invasive strabismus surgery (MISS) with the fornix approach in paediatric horizontal strabismus surgery (<12 years) and to evaluate early postoperative inflammation, visual acuity and operating time after a four-year training period...
Bisphosphonates can cause orbital inflammation
1 April 2016
| Claire Howard
|
EYE - Neuro-ophthalmology
|
Bisphosphonate, complication, orbital inflammation, orbital inflammatory syndrome, side effect, zolendronate
The authors describe four patients with bisphosphonate induced orbital inflammation and review a further 25 cases in the literature. Intravenous zoledronate was the most common precipitant (76% of cases) with the mean time until onset of inflammation being three days...
