Bromfenac versus betamethasone in diabetic macular oedema
31 October 2023
| Kurt Spiteri Cornish
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EYE - Vitreo-Retinal
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Diabetic macular edema, betamethasone, bromfenac, central subfield thickness, intraocular pressure
This is a randomised, prospective, single-centre trial in patients diagnosed with diabetic macular oedema (DMO) with central subfield thickness (CST) of 250-500µm, who refused anti-VEGF treatment. Nineteen eyes of 19 patients were randomised to bromfenac (BF) or betamethasone (BM) drops,...
OCT findings after strabismus surgery for macular, choroidal and nerve fibre thickness
3 October 2022
| Fiona Rowe (Prof)
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Paediatric Ophthalmology / Strabismus
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Choroidal thickness, macular thickness, optical coherence tomography, strabismus surgery
This study used OCT to investigate the changes in the central macular thickness, subfoveal choroidal thickness (SFCT) and retinal nerve fibre layer (RNFL) after horizontal rectus surgery for patients with strabismus. This was a retrospective study and patients were grouped...
Retinal changes prior to hydroxychloroquine toxicity
1 October 2021
| Ed Rule
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EYE - Vitreo-Retinal
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Ganglion cell layer, Hydroxychloroquine, Optical coherence tomography, Retina, Retinal thickness
In this retrospective longitudinal study, the authors examined changes in retinal layer thickness in patients taking hydroxychloroquine without evidence of retinopathy. Patients were drawn from a hydroxychloroquine screening clinic and required at least two OCT scans, at least one year...
Comparison of changes in ECD and CCT between CPS and FLACS
5 June 2020
| Jonathan Chan
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EYE - Cataract, EYE - Refractive
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ECD, FLACS, corneal thickness, endothelial cell density, femtosecond laser, phacoemulsification
This is an intraindividual randomised clinical trial of 134 eyes from 67 patients, one eye was treated with femtosecond laser-assisted cataract surgery (FLACS) (including pretreatment of main incision, side port, capsulotomy and lens fragmentation) and the fellow eye received conventional...
Choroidal thickness in strabismus and amblyopia
1 June 2018
| Fiona Rowe (Prof)
|
Paediatric Ophthalmology / Strabismus
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amblyopia, anisometropia, choroidal thickness, esotropia, exotropia
The authors examined the effect of exotropia, esotropia, anisometropic amblyopia and hypermetropia on choroidal thickness in a prospective cross section study. The study included 100 patients and 20 controls with a mean age of 8.5±2.9 years; 61 female and 59...
Steroid implants in the treatment of post-epiretinal membrane peel macular oedema
1 February 2018
| Kurt Spiteri Cornish
|
Retina / Uvea / Vitreous
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Central retinal thickness, Dexamethasone implant, Fluocinolone acetonide implant, Intravitreal steroid implants, Long-term outcome, Macular pucker surgery, Membrane peeling, Pars plana vitrectomy, Persistent macular edema
This is a retrospective review of 39 eyes of 37 patients treated with Ozurdex® (intravitreal dexamethasone implant) for persistent post-operative cystoid macular oedema (CMO) following vitrectomy and idiopathic epiretinal membrane (ERM) peeling. The 0.7mg implant was injected in each eye...
Using OCT to screen and monitor Alzheimer’s disease
1 June 2016
| Claire Howard
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EYE - Neuro-ophthalmology
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Macular thickness, mild cognitive impairment, optical coherence tomography, subjective memory complaints
Alzheimer’s disease (AD) is a neurodegenerative illness characterised by progressive decline in cognitive function. AD is the main cause of dementia worldwide. Over recent years researchers have strived to find biomarkers to diagnose AD, particularly in the early stages of...
Choroidal and RNFL thickness in patients with OSAS
1 August 2015
| Anjali Gupta
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Retina / Uvea / Vitreous
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choroidal thickness, obstructive sleep apnoea syndrome, spectral-domain optical coherence tomography
In obstructive sleep apnoea syndrome (OSAS), hypoxia secondary to repetitive apnoeic episodes leads to blood pressure variations and haemodynamic changes. There is also intermittent activation of the sympathetic system when the patient is aroused from sleep during apnoeic episodes. OSAS...
Structural effects of migraine on the retina
1 June 2015
| Claire Howard
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EYE - Neuro-ophthalmology
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Migraine, retinal nerve fibre layer thickness, spectral-domain optical coherence tomography
Migraine is a common, chronic, multifactorial neuro-vascular disorder typically characterised by recurrent attacks of disabling headache and autonomic nervous system dysfunction (migraine without aura). Up to one third of patients also have neurological aura symptoms (migraine with aura). The objective...
Nicotine accelerates diabetes induced retinal changes
1 June 2015
| Khadijah Basheer
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Retina / Uvea / Vitreous
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Diabetes, SD-OCT, SLO, neurons, nicotine, retinal thickness
This study investigated the influence of nicotine in an experimentally induced diabetic rat model. They used non-invasive high-resolution spectral domain optical coherence tomography (SD-OCT) imaging to provide quantitative information on the temporal alterations of retinal structures at the micrometer resolution...
Short-term effects of intravitreal bevacizumab on the cornea
1 December 2014
| Khadijah Basheer
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EYE - Cornea, EYE - General
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anterior chamber depth, bevacizumab, central corneal thickness, intraocular pressure, iridocorneal angle, simulated keratometry
Bevacizumab has been extensively used to treat macula oedema and neovascularisation of the retina and it has also been useful in the management of corneal neovascular diseases. This prospective study aimed to provide more information on the effect bevacizumab may...
Choroidal thickness in ocular sarcoidosis by OCT measurement
1 December 2014
| Nikolaos D Georgakarakos
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Retina / Uvea / Vitreous
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Choroidal thickness, enhanced depth imaging optical coherence tomograph, quiescent phase, sarcoidosis, uveitis
This is the first study to evaluate the choroidal thickness in patients with ocular sarcoidosis during the quiescent phase using enhanced depth imaging optical coherence tomography (EDI-OCT) and comparing with normal subjects. Ocular sarcoidosis may affect the choroidal circulation (occlusive...
