Journal Reviews
Incomplete teprotumumab treatment for thyroid eye disease
This is a multi-centre retrospective analysis of clinical outcomes in patients who were on teprotumumab for thyroid eye disease but had the usual regime of eight infusions, three weeks apart, interrupted due to COVID-19. Manufacturing was suspended between Dec 2020...
Outcomes of reinjection of Ranibizumab for reactivation of retinopathy of prematurity
The authors present their data from Egypt assessing the effects of Ranibizumab reinjection for neonates with retinopathy of prematurity (ROP). Doses given were 0.25mg/0.025mL. They screened 2318 infants with 115 (5%) of infants with a mean post menstrual age (PMA)...
Cycloplegic autorefraction versus cycloplegic retinoscopy
This cross-sectional study compared cycloplegic autorefraction using VISUREF 100 table top and keratometer device (Zeiss) versus cycloplegic retinoscopy. The study included 47 children (94 eyes) of which 55 eyes were excluded because of ocular disease or not aged three to...
Characteristics of age-related distance esotropia
The primary aim of this study was to describe clinical characteristics and natural history of age-related distance esotropia (ARDET) within an adult cohort over a 20-year period. This was a retrospective review of 73 patients from 751 with adult onset...
Saccadic measurements in intermittent exotropia vs fusional amplitude
The authors investigated the correlation between fusional convergence amplitude and saccades during the shift from exotropia to binocular fixation during the cover / uncover test. This was an observational study of 15 patients (six female, nine male) with intermittent exotropia....
Four rectus muscle surgery for infantile nystagmus syndrome
The authors present a case report of infantile nystagmus syndrome (INS) with abnormal head posture (AHP) of face turn, head tilt and chin depression with a single-step surgery of all four horizontal rectus muscles. The case was a 26-year-old male...
Features of childhood cases of sixth nerve palsy
Based on limited information available for cranial nerve palsies in children, the authors aimed to collect data on new onset paediatric sixth nerve palsies in a UK population. This was a retrospective study over 10 years for children aged <18...
Review of bupivacaine use in treatment of strabismus
This review aimed to assess the applications of bupivacaine (B) in the non-surgical treatment of strabismus in human and animal studies. Animal studies show that singly-innervated fibres with low concentrations of mitochondria and developed sarcoplasmic reticulum are more affected by...
How reliable is the postoperative diplopia test and can it predict postoperative outcomes?
A two-phase process evaluating the postoperative diplopia test is presented. A standardised operating procedure was used for conducting all postoperative diplopia tests for this study which is described in the paper. Phase one focused on reliability, test-retest and interobserver. Adults...
Visual acuity outcomes after cataract surgery in type 2 diabetes (NIDDM): the action to control cardiovascular risk in diabetes (ACCORD) study
This is a retrospective case-control study of 1136 eyes enrolled in the 784 ACCORD patients receiving cataract surgery between 2001-2014. 362 / 1136 eyes had gradable fundus photography for diabetic retinopathy (DR). Seven hundred and sixty-two eyes (67.1%) achieved 20...
Sex hormones in males and females with central serous chorioretinopathy
This study was aimed to assess the role of sex hormones in male and female patients with central serous chorioretinopathy (CSC), a disease with a pronounced male predilection. Two hundred and six patients, 183 males (mean age 52, median 52,...
Gene therapy: perspectives from young adults with Leber’s congenital amaurosis
The authors present their telephone survey data of 10 patients with a mean age of 24.4 years regarding their opinion on gene therapy for their Leber’s congenital amaurosis. Patients were recruited at the Hospital for Sick Children, Toronto. Of the...
