Long-term retinal changes following unilateral retrobulbar optic neuritis
1 June 2015
| Claire Howard
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Neuro-Ophthalmology
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OCT, optic neuritis, optical coherence tomography, RNFL, steroid
The aim of this study was to assess the longitudinal changes in retinal nerve fibre layer (RNFL) thickness after a first attack of optic neuritis and to investigate the impact of treatment on RNFL thinning at one year after the...
Effect of anti-VEGF treatment on PED morphology
1 June 2015
| Jaya Myneni
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Retina / Uvea / Vitreous
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Choroidal neovascularization, optical coherence tomography, ranibizumab, VEGF
This retrospective study of 30 eyes assessed the effect of anti-VEGF on morphology of pigment epithelial detachments (PED) secondary to age-related macular degeneration (AMD). Thirty eyes of 28 patients with PED were compared to 30 eyes of 30 patients with...
Choroidal and macular thickness in nonarteritic anterior ischaemic optic neuropathy
1 December 2014
| Claire Howard
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Neuro-Ophthalmology
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Choroidal thickness, enhanced depth imaging, macular thickness, nonarteritic anterior ischemic optic neuropathy, optical coherence tomography
This study evaluates the choroidal and macular thickness in patients with chronic nonarteritic anterior ischaemic optic neuropathy (NA-AION). Two groups of subjects were compared, group one included 20 eyes with chronic NA-AION and group two, 31 healthy control eyes. The...
Correlation between structural and functional status of optic nerve and retina in multiple sclerosis
1 August 2014
| Claire Howard
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Neuro-Ophthalmology
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Multiple sclerosis, optical coherence tomography, perimetry, retinal nerve fibre layer thickness, visual evoked potentials
Multiple sclerosis (MS) involves autoimmune inflammatory demyelination and axonal degeneration in the central nervous system. Investigation of the retina and optic nerve head (ONH) is an ideal way to visualise this demyelination. This study investigates the functional and structural properties...
Optical coherence tomography in patients exposed to vigabatrin
1 August 2014
| Nana Theodorou
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Retina / Uvea / Vitreous
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anti-epileptic drug, drug toxicity, full-field electroretinography, optical coherence tomography, vigabatrin, visual field defect
Vigabatrin is used to treat epilepsy and can lead to increased levels of gamma-aminobutyric acid (GABA) in the brain and in the retina leading to binasal visual field defects. Although not the first line of treatment for adults it is...
Spectral domain OCT vs. confocal scanning laser ophthalmoscope in measuring RNFL thickness
1 June 2014
| Anjali Gupta
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Ophthalmology
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Cirrus optical coherence tomography, Heidelberg retinal tomograph 3, retinal nerve fibre layer thickness
The aim of this prospective study was to compare the retinal nerve fibre layer thickness (RNFL) measurements obtained from the Cirrus optical coherence tomography (spectral domain OCT) with the Heidelberg Retinal Tomograph 3 (HRT3, confocal scanning laser ophthalmoscope). Eighty-eight normal...
Exudative age-related macular degeneration
1 April 2014
| Nana Theodorou
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Retina / Uvea / Vitreous
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neovascular age-related macular degeneration, exudative age-related macular degeneration, fluorescein angiography, microperimetry, optical coherence tomography
The authors looked at macular lesions in eyes with newly diagnosed exudative age-related macular degeneration. The eyes of 23 patients were included and tested for visual acuity, contrast sensitivity, microperimetry, optical coherence tomography (OCT) and fluorescein and indocyanine green angiography....
Density of cataract and its influence on retinal nerve fibre layer thickness
1 December 2013
| Nana Theodorou
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Retina / Uvea / Vitreous
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cataract, image quality, optical coherence tomography, retinal nerve fibre layer
The aim of this study was to further define and model the influence of cataract on spectral domain optical coherence tomography (SDOCT) image quality and retinal nerve fibre layer (RNFL) thickness measurements. OCT quality is influenced by opacities in the...
