ANGPTL-4 inhibition reduces inflammation in diabetic retinopathy
1 June 2018
| Graham Wallace
|
Retina / Uvea / Vitreous
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Adipocytokine, Angiopoietin-like protein-4 (ANGPTL-4), Diabetic retinopathy (DR), Hypoxia inducible factor-1 alpha (HIF-1α), Inflammation, Profilin-1
Diabetic retinopathy (DR) is the most common cause of blindness in working-age humans, and numbers are rising due to increased cases of type 2 diabetes (T2D). T2D is associated with increased obesity and dyslipidaemia, which is a major risk factor...