Leber’s hereditary optic neuropathy: from lab to clinic
1 October 2016
| Chrysostomos D Dimitriou
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EYE - Neuro-ophthalmology
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Hereditary optic neuropathy, Leber hereditary optic neuropathy, mitochondrial optic neuropathy, optic neuropathy
Leber’s hereditary optic neuropathy (LHON) was the first clinically described mitochondrial disorder (1871). This article reviews the pathophysiology and clinical features of LHON with a focus on translational research. G11778A is currently the most common mutation worldwide and is associated...
