Prognostic factors for visual acuity in patients with LHON after gene therapy
5 February 2020
| Ivan Yip
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Retina / Uvea / Vitreous
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Leber's hereditary optic neuropathy, ND4, gene therapy, prognosis
This retrospective study investigates prognostic factors affecting the visual acuity after a single intravitreal injection of rAAV2-ND4 gene therapy in 53 patients with Leber’s hereditary optic neuropathy (LHON) with mutation at site 11 778. Patients were reviewed one and three...