Cataract progression after Nd-YAG laser iridotomy in primary angle-closure suspect eyes
2 February 2024
| Jonathan Chan
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EYE - Glaucoma
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Angle, Clinical Trial, Glaucoma, Treatment Lasers, Vision
A total of 889 of eligible bilateral primary angle-closure suspect (PACS) patients were recruited from the Zhongshan Angle Closure Prevention Trial. One randomly selected eye received laser peripheral iridotomy (LPI), while the fellow remained untreated. Cataract was graded by the...
Treatment outcomes for retinal detachment
This is a retrospective, nationwide, multicentre study with retinal detachment (RD) in the Japan-RD registry between 2016 to 2017. The primary outcome was the estimated mean difference of postoperative corrected visual acuity (CVA) in six months and a propensity score...
Practice patterns of uveal melanoma management with Iodine-125 brachytherapy
5 August 2020
| Annes Ahmeidat
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EYE - Pathology, EYE - Oncology
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Brachytherapy, Treatment practices, Uveal melanoma
With the 2006 Collaborative Ocular Melanoma Study Group (COMS) study demonstrating no difference in survival outcomes for participants randomised to either iodine-125 brachytherapy or enucleation, the majority of primary uveal melanomas in the United States are now treated with brachytherapy....
Quality of life measurement in amblyopia
5 June 2020
| Fiona Rowe (Prof)
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Paediatric Ophthalmology / Strabismus
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Amblyopia, Quality of life, Questionnaire, Treatment
This study aimed to explore the psychometric properties of the CATQoL instrument and to determine the ability of it to measure the impact of amblyopia treatment from a child’s perspective. A total of 342 children were recruited with analysis presented...
Intracameral mydriasis with Mydrane
1 December 2018
| Jonathan Chan
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EYE - Cataract, EYE - Refractive
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Lens And Zonules, Pharmacology, Pupil, Treatment Surgery
The aim of this study is to evaluate the ‘real world’ experience in a UK setting for intracameral Mydrane mydriasis in routine cataract surgery. A prospective consecutive series of 60 patients (group 2) had intraoperative, intracameral Mydrane (tropicamide 0.02%, phenylephrine...
Radiation maculopathy
1 December 2018
| Jonathan Chan
|
Retina / Uvea / Vitreous
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Inflammation, Macula, Pathology, Retina, Treatment Medical
This is a retrospective non-randomised study of 13 consecutive eyes of 13 patients affected by radiation maculopathy secondary to eye irradiation for primary uveal melanoma (Iodine-125 brachytherapy). All patients were treated with a single intravitreal 0.7mg dexamethasone implant and full...
2018 update on intravitreal injections
1 December 2018
| Sofia Rokerya
|
Retina / Uvea / Vitreous
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Intravitreal injections, Treatment of retinal diseases, Vitreoretinal diseases
In this review article the authors have highlighted the standardised and structured approach to intravitreal injections (IVI) by examining the recent evidence-based literature. IVI is the most commonly performed procedure worldwide with low potential risk of endophthalmitis. IOP spikes are...
IAC vs. IVC chemotherapy for RB
1 April 2018
| Jonathan Chan
|
Paediatric Ophthalmology / Strabismus
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Child health (paediatrics), Neoplasia, Retina, Treatment Medical
This a single centre retrospective review of consecutive patients between 1997 and 2014, of all sporadic unilateral retinoblastoma (RB) group D cases, treated with combined intravenous chemotherapy (IVC) and focal treatments (1997- 2008), or intra-arterial chemotherapy (IAC) treatment (2008 to...
Conversion factors for fovea on / off detachments
This is a retrospective study of medical records in a single unit over a 14 year period from January 2001 – December 2014, of patients who converted from fovea-on to fovea-off rhegmatogenous retinal detachment (RRD). Ten cases were identified while...
Treatment of severe chronic ocular graft-versus-host disease
1 February 2018
| Jonathan Chan
|
EYE - Cornea, EYE - General
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Cornea, Inflammation, Treatment Medical, Wound healing
A retrospective study from Cologne, Germany, between November 2012 to March 2015, of 17 patients with graft-versus-host disease (GVHD) treated with 100% single use vials autologous serum eye drops in sealed system. Visual acuity, corneal staining, frequency of artificial tears,...
Clinical outcomes of AMT in acute ocular chemical injury
1 August 2017
| Jonathan Chan
|
EYE - Cornea, EYE - General
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Cornea, Inflammation, Ocular surface, Stem Cells, Treatment Surgery
This is a retrospective study of patients from two units in Germany and UK between 1998 and 2008. The ocular chemical burns were classified by Roper-Hall and Dua classifications. A total of 72 eyes of 54 patients aged 37.3 years...
Propranolol treatment of infantile haemangioma
1 October 2016
| Jonathan Chan
|
Paediatric Ophthalmology / Strabismus
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Child health (paediatrics), Drugs, Pharmacology, Treatment Medical
This is a retrospective review of 104 patients treated for infantile haemangioma between January 2009 and July 2012. All patients underwent pretesting either with protocol A (administration of test dose with routine observations) or protocol B (cardiology clinic assessment, including...
