Ovarian hormones drive onset of Sjogren’s disease in mice
1 December 2014
| Graham Wallace
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Cornea / External Eye Disease
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Sjögren’s Syndrome, lacrimal glands, sex hormones, cytokines, anti-Ro/SSA, anti-La/SSB, NOD.B10.H2b
Sjogren’s syndrome (SS) is a debilitating, sight-threatening, systemic autoimmune disease with no effective treatment available. SS is characterised by lacrimal gland lymphocytic infiltration and epithelial cell death, as well as by the presence of serum autoantibodies. Patients have severe dry...