Differentiating orbital cellulitis from non-specific orbital inflammation
4 December 2023
| Hetvi Bhatt
|
Oculoplastics, Orbit
|
C-Reactive protein, Non-specific orbital inflammation, inflammatory markers, orbital cellulitis, white-cell count
This is a retrospective study looking at whether common laboratory investigations can help differentiate between orbital cellulitis (OC) and non-specific orbital inflammation (NSOI). NSOI is a diagnosis of exclusion following negative investigations for systemic diseases such as IgG4-related disease, granulomatosis...
High rate of conversion from ocular hypertension (OH) to glaucoma (UG) in subjects with uveitis
5 June 2023
| Jonathan Chan
|
Glaucoma
|
glaucoma, infection, inflammation, treatment medical, treatment surgery
This is a retrospective study from Auckland over a 10-year period including 188 eyes of 139 subjects with either OH or UG and were included for analysis with a mean follow-up of 9.9 years. The most common uveitis causes were...
High rate of conversion from ocular hypertension to glaucoma in subjects with uveitis
3 April 2023
| Jonathan Chan
|
Glaucoma
|
glaucoma, infection, inflammation, treatment medical, treatment surgery
This is a retrospective study from Auckland over a 10-year period. A total of 188 eyes of 139 subjects with either ocular hypertension (OH) or uveitic glaucoma (UG) were included for analysis with a mean follow up of 9.9 years....
Inflammation and microvascular changes in diabetic retinopathy
1 February 2022
| Kurt Spiteri Cornish
|
Retina / Uvea / Vitreous
|
Aqueous flare, diabetes mellitus, diabetic retinal neuropathy, diabetic retinopathy, intraocular inflammation, neuroinflammation
Studies have shown that neurodegeneration and inflammation in the retina start early in diabetic retinopathy (DR) and can be present before the latter is clinically evident. The aim of this retrospective review of 99 diabetic patients was to evaluate retinal...
A novel way to distinguish between types of anterior ischaemic optic neuropathy
7 April 2021
| Claire Howard
|
Neuro-Ophthalmology
|
Anterior ischaemic optic neuropathy, inflammation, monocyte to high-density lipoprotein ratio
The authors evaluate the monocyte to high-density lipoprotein (HDL) ratio (MHR) in patients with arteritic and non arteritic anterior ischaemic optic neuropathy (A-AION / NA-AION). A distinction between the two types of AION is essential to begin appropriate treatment, which...
Topical nonsteroidal ant-inflammatory drugs (NSAIDs) in patients undergoing cataract surgery
4 February 2021
| Kurt Spiteri Cornish
|
EYE - Cataract, EYE - Refractive
|
Postoperative inflammation, cataract surgery, diclofenac, laser flare meter, nepafenac
Inflammation is a major risk factor for the development of cystoid macular oedema (CMO) after cataract surgery, leading to breakdown of the blood-retina barrier. There is a correlation between severity of CMO and level of postoperative inflammation. Laser flare meter...
Orbital manifestations of granulomatosis with polyangitis
4 February 2021
| Rina Bhatt
|
Oculoplastics, Orbit
|
Granulomatosis with polyangiitis, Orbital granulomatosis, Wegener disease, orbital inflammation, orbital tumors
This a retrospective, observational study where authors looked at the ophthalmological examination, biopsy, antibodies and CT scan results of all patients diagnosed with granulomatosis with polyangitis (GPA) from January 2007-January 2019. Out of 101 patients with diagnosis of GPA, 15...
IOP in children with uveitis
1 August 2019
| Jonathan Chan
|
Retina / Uvea / Vitreous
|
child health (paediatrics), glaucoma, inflammation, uveitis
This is a retrospective study of paediatric uveitis (<16-years-old) between July 2002 to June 2016 of a total of 320 children from a single centre: 17.2 % (55/320 patients) developed raised IOP requiring therapy; 11.5% of eyes required glaucoma surgery...
Diclofenac versus Bromfenac after cataract surgery
1 April 2019
| Kurt Spiteri Cornish
|
EYE - Cataract, EYE - Refractive
|
Non-steroidal anti-inflammatory drugs, bromfenac, cataract surgery, diclofenac, intraocular inflammation
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used after cataract surgery to reduce inflammation and cystoid macular oedema (CMO). Diclofenac 0.1% is used three to five times daily for 28 days and Bromfenac 0.09% twice daily for 14 days postoperatively. The...
Features of Behcet’s disease
This is a retrospective single centre study from Paris, France, between the periods of 1986 to 2015. Twenty-nine out of 217 (13.3%) neuro-Behcet’s disease (NBD) patients presented with neuro-ophthalmic manifestations (55% of men and mean age of 28 years). Sixteen...
Review of extraocular muscle biopsies and utility of biopsy in extraocular muscle enlargement
1 February 2019
| Jonathan Chan
|
Oculoplastics, Orbit
|
inflammation, muscles, neoplasia, pathology
This is a retrospective case series study from Melbourne, Australia, of 93 patients with extraocular muscle (EOM) enlargement who underwent an EOM biopsy between March 1992 and January 2017. Statistical analysis was performed to compare the data between patients with...
Meta-analysis of HLA B27 associated acute anterior uveitis
1 August 2018
| Mrinal Rana
|
Retina / Uvea / Vitreous
|
Ankylosing spondylitis, fibrin, glaucoma, hypopion, ocular inflammation
A literature-based meta-analysis was carried out to look at the various clinical features associated with HLA- B27 acute anterior uveitis (AAU). After an extensive search of literature for HLA B27 uveitis was conducted, 735 results were obtained. Twenty-nine articles were...
