Journal Reviews

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Outcomes from evisceration with primary implant in 1800 patients

3 April 2023 | | Oculoplastics, Orbit | ig data, electronic medical records, epidemiology, evisceration, exposure, extrusion, implant, migration, orbit, prosthesis, ptosis, risk factors, socket

This is a retrospective analysis of 1800 patients who had evisceration with orbital implant between 2013-2019. As the largest published series on this topic, the authors are able to give relatable real-world data on complications following surgery. They use a...

MicroRNA mediate retinoblastoma signal transduction

1 October 2014 | | Retina / Uvea / Vitreous | KEGG, cell migration, colony formation, microRNA-21, phosphorylation signaling pathway, retinoblastoma, seed-targeting, tiny anti-miRNA

MicroRNAs (miR) are small non-coding single-stranded RNA molecules, normally 22 nucleotides long. There is a large family of miR that control protein expression by binding to mRNAs, leading to their degradation. One important role of miR is in tumours where...