Does methanol poisoning require ophthalmic investigation?
2 February 2024
| Claire Howard
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EYE - Neuro-ophthalmology
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Methanol poisoning, acute poisoning, case series, ocular findings, outbreak
The authors report a case series of 21 patients (41 eyes) diagnosed with acute methanol poisoning following an outbreak in Tunisia in 2020. All patients underwent a complete ophthalmological examination including visual fields, colour vision test and optical coherence tomography...
Ocular manifestations of Whipple’s disease
2 February 2024
| Lucy Osborne
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Retina / Uvea / Vitreous
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Granulomatous uveitis, Whipple’s disease, infectious uveitis, ocular infection, tropheryma whipplei
In this retrospective review of 217 patients with Whipple’s disease (WD), the authors reviewed the presentations of those with ocular manifestations. Ocular signs of WD are under recognised, frequently resulting in misdiagnosis and mismanagement. Mayo Data Explorer, a Mayo Clinic...
Tutopatch® in surgical management of third nerve palsy
31 October 2023
| Fiona Rowe (Prof)
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Paediatric Ophthalmology / Strabismus
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Extra-ocular muscles surgery, lyophilized bovine pericardium (Tutopatch®), re-operations for third nerve palsy
his study evaluates the benefit of using Tutopatch® to elongate the extraocular muscles in patients with third nerve palsy who have residual strabismus after unsuccessful surgery and no other surgical options considered to be appropriate. The study included nine patients...
Bromfenac versus betamethasone in diabetic macular oedema
31 October 2023
| Kurt Spiteri Cornish
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Retina / Uvea / Vitreous
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Diabetic macular edema, betamethasone, bromfenac, central subfield thickness, intraocular pressure
This is a randomised, prospective, single-centre trial in patients diagnosed with diabetic macular oedema (DMO) with central subfield thickness (CST) of 250-500µm, who refused anti-VEGF treatment. Nineteen eyes of 19 patients were randomised to bromfenac (BF) or betamethasone (BM) drops,...
Rare presentation of giant cell arteritis in Chinese subjects
1 September 2023
| Claire Howard
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EYE - Neuro-ophthalmology
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non-arteritic anterior ischaemic optic neuropathy, Chinese, central retinal artery occlusion, Giant cell arteritis, ocular ischaemic syndrome, posterior ischaemic optic neuropathy
Only a few case reports of biopsy-proven GCA (BpGCA)-associated vision loss in Chinese subjects have been published. This paper presents three elderly Chinese subjects with BpGCA who presented with vision loss. A search of the literature was also conducted to...
Glaucoma medications and ocular surface disease
3 August 2023
| Su Young
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EYE - Glaucoma
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Drug allergy, OSD, drug toxicity, drug-induced cicatricial keratitis, dry eye, glaucoma medications, ocular surface disease
This literature review examined ocular surface disease (OSD) associated with glaucoma medication. The authors examined the prevalence of features and management guidelines glaucoma medication associated OSD. Fifty-eight articles published within the past five years are included in this review and...
Ocular hypertension following intravitreal steroid injections: a comparative study between triamcinolone-acetonide and dexamethasone-implant
3 April 2023
| Sofia Rokerya
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Retina / Uvea / Vitreous
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Dexamethasone-implant, Glaucoma, Intravitreal steroid-induced ocular hypertension, Risk factors for steroid-induced ocular hypertension, Triamcinolone-acetonide
This was a retrospective observational study of steroid response following 1549 intravitreal steroid (TA and Dex) injections. One thousand and seventy-five eyes of 897 patients were reviewed. Glaucoma patients, glaucoma suspects, uveitis, trauma, and cases with less than one month...
Literature review on the use of bupivacaine for strabismus management
3 February 2023
| Fiona Rowe (Prof)
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Paediatric Ophthalmology / Strabismus
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Bupivacaine, extraocular muscles, strabismus
The purpose of this study was to examine the overall efficacy of bupivacaine (BPX) when used in isolation for the treatment of strabismus. This was a literature review from 1980 to 2021. The search identified 196 papers of which eight...
RCT review of surgery for open angle glaucoma
1 December 2022
| Su Young
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EYE - Glaucoma
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Intraocular pressure, Open angle glaucoma, meta-analysis, microstent, phacoemulsification
This systematic review and meta-analysis examined eight randomised controlled trials (RCTs) to compare the intraocular pressure (IOP) reducing effect of three types of microstent implantation (Hydrus, iStent, CyPass) combined with phacoemulsification versus phacoemulsification alone for patients with open-angle glaucoma (OAG)...
Review of the use of amniotic membrane in restrictive strabismus
3 October 2022
| Fiona Rowe (Prof)
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Paediatric Ophthalmology / Strabismus
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Strabismus, amnion, eye movements, ocular motility disorders, ophthalmologic surgical procedures
This literature review was undertaken to investigate the indications, complications and final results of amniotic membrane (AM) transplantation in ocular motility restrictions. The review (of 1103 papers) outlines the healing process plus use of AM. Excluded papers were those of...
Detection of SO tendon abnormality versus atrophy
3 October 2022
| Fiona Rowe (Prof)
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Paediatric Ophthalmology / Strabismus
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Extraocular muscle anatomy/histopathology/physiology, magnetic resonance imaging, strabismus, superior oblique palsy
This study aimed to evaluate patterns of binocular misalignment in primary gaze, lateral and vertical gaze, and head tilt in patients showing head-tilt dependent hypertropia associated with discontinued superior oblique (SO) tendon but without SO muscle atrophy, versus patients with...
Augmented surgery for monocular elevation deficiency
1 June 2022
| Fiona Rowe (Prof)
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Paediatric Ophthalmology / Strabismus
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Monocular elevation deficiency, lateral rectus transposition, posterior fixation suture, single horizontal muscle transposition
The outcomes are described for augmented lateral rectus superior transposition in cases of acquired monocular elevation deficiency (MED) associated with large hypotropia in primary gaze. The lateral rectus was transposed superiorly and reinserted on sclera between the temporal margin of...
