Reporting and representation of race and ethnicity in paediatric ophthalmology clinical trials
This systematic review aimed to identify the prevalence and factors associated with the reporting of race / ethnicity data in paediatric ophthalmology studies and how this has changed over time. A systematic search strategy to find randomised controlled trials between...
Saccadic duration and trajectories in monkeys with induced strabismus
This author aimed to (1) determine whether saccadic duration is consistently the same for the two eyes and / or whether the amplitude-duration relationships differ for the two eyes; and (2) test the hypothesis that saccade trajectories show abnormally large...
Long-term treatment for diabetic macular oedema
2 April 2025
| Kurt Spiteri Cornish
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EYE - Vitreo-Retinal
The authors set out to characterise anti-VEGF treatment patterns and long-term outcomes in patients with diabetic macular oedema. A retrospective analysis of over 190 thousand patients on the Intelligent Research in Sight registry was performed. Of these, 1236 eyes have...
Under pressure: the constant drive to improve IOP monitoring
1 April 2025
| Zhihang Cheng
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EYE - Glaucoma
The authors offer a comprehensive overview of interplay between glaucoma and intraocular pressure (IOP), IOP measurement principles and historical measurement techniques and progress in IOP measurement devices. The authors explore the issues surrounding current thinking in IOP measurement and its...
Efficacy of augmented-dosed surgery versus botulinum toxin A injection for acute acquired concomitant esotropia
This is a retrospective study of 104 patients diagnosed with acute acquired concomitant esotropia (AACE) between 2020 and 2022. Potential factors that influence the dose-response of bilateral medial rectus recession (MRec) and the rate and risk factors for ACCE relapse...
Sirolimus for lymphatic-venous malformation
This is a case report on the use of oral sirolimus in the treatment of lymphatic-venous malformations. This condition can often be sight-threatening when present in the orbit and traditional management options have included observation, sclerotherapy and surgery. Both sclerotherapy...
Amblyopia information provided by chatbots – how readable and understandable is this?
The purpose of this study was to evaluate the understandability, actionability and readability of responses to frequently asked questions about amblyopia provided by ChatGPT-3.5, Bing Chat, Bard and the American Association for Pediatric Ophthalmology and Strabismus (AAPOS) website, along with...
Horizontal recti injection of botulinum toxin for treatment of infantile nystagmus
In this study the authors aimed to demonstrate the effect of botulinum toxin (BT) on the frequency of ocular oscillation in children with infantile nystagmus syndrome (INS). Botulinum toxin was administered with direct injection into the horizontal recti muscles using...
Risks for ROP development in mid and late preterm infants
The authors evaluated the incidence, risk factors and retinopathy of prematurity (ROP) development in mid and late preterm infants born at 32 to <37 weeks of gestational age (GA). This was a retrospective study of 5477 infants: 54.4% male. Overall,...
Risks of advanced ROP development in unscreened babies
The authors report a retrospective study of the prevalence of infants with stage 4b and 5 retinopathy of prematurity (ROP) who were never screened and the importance of screening guidelines. The study was conducted in a tertiary eye hospital in...
How common is empty sella in neuro-ophthalmology patients not suspected of raised intracranial pressure
28 February 2025
| Lauren R Hepworth
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EYE - Neuro-ophthalmology
The study aimed to assess how common the presence of empty / partially empty sella is amongst neuro-ophthalmology patients undergoing magnetic resonance imaging (MRI) excluding for papilledema and raised intracranial pressure (ICP). The study retrospectively reviewed case records of consecutive...
The effect of orbital decompression on upper eyelid retraction
This is a systematic review and meta-analysis on whether there is a change in upper lid retraction following orbital decompression. Traditional teaching states that the order of surgery for thyroid eye disease should be decompression firstly, followed by squint surgery...
