The authors present eight cases of ocular neuromyotonia (ONM) with an overview of the pathophysiology, aetiology, clinical presentations and possible treatments. Diagnosis was made only after thorough and repeated orthoptic examinations and review of medication history. An overview of the literature revealed 49 cases with ages of 7-77 years (cases presented in this study were aged 39-78 years of which seven were female). In the literature, 75% were female. VI and III nerves were commonly affected and tumours were commonly in sellar or parasellar regions. Fifty-five percent of cases followed irradiation treatment. TED was the second most common cause. Treatment was typically with carbamazepine. The cases presented in this study included eight III and one VI nerve palsy. Two cases had TED and 50% had history or irradiation treatment. One had hypovitaminosis D.
Ocular neuromyotonia features
Reviewed by Fiona Rowe
Ocular neuromyotonia: case reports and literature review.
CONTRIBUTOR
Fiona Rowe (Prof)
Institute of Population Health, University of Liverpool, UK.
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