Saccadic duration and trajectories in monkeys with induced strabismus
Reviewed by Fiona Rowe

This author aimed to (1) determine whether saccadic duration is consistently the same for the two eyes and / or whether the amplitude-duration relationships differ for the two eyes; and (2) test the hypothesis that saccade trajectories show abnormally large curvature in monkeys with experimentally induced pattern strabismus. The study involved six rhesus monkeys: two with normal eye alignment, two with exotropia and two with esotropia. Two had A pattern exotropia of 25–40 degrees and 20–25 degrees. Two had A pattern esotropia (2–15 and 10–25 degrees). The findings of the study were that saccade durations in a subset of trials for monkeys with strabismus differed for the two eyes by 10ms or more, in apparently non-drowsy state. Further, saccadic curvature was generally within the normal range for monkeys with strabismus but often differed for the two eyes unlike normal controls. The author concludes that, in strabismus, saccadic durations can differ for the two eyes by an abnormally large amount.

Disconjugacies of saccade duration and trajectories in strabismus.
Walton MMG.
STRABISMUS
2024;32(4):252–70.