Journal Reviews
Effects of clonidine vs. placebo
The purpose of this study was to measure postoperative agitation using a standardised scale and evaluate whether it is reduced if given clonidine prior to strabismus surgery as compared to placebo. The scales included the Pediatric Anesthesia Emergence Delirium (PAED)...
Piggyback toric IOLs in complex cases
This study evaluates the outcome of toric sulcus fixated lenses (MS 614/714 TPB (Human Optics, Germany) in 21 eyes with high astigmatism. The cases included previous penetrating keratoplasty (n=15), post cataract surgery astigmatism (n=3), rotation of in-the-bag toric IOL (n=1),...
Errors in refractive surgery
A retrospective case series looking at sources of errors in patients undergoing laser refractive surgery. Twenty-two cases of error were identified in 18 patients; 15 were unilateral, three bilateral and two errors occurred in the same eye (on attempting correction...
Culture positivity of needles for IVT injections
Given the worldwide use of intravitreal (IVT) injections, the authors of this paper set out to evaluate the rate of culture positivity of the needles used in routine IVT injections and compare this positivity between 27-gauge and 30-gauge needle tips....
Molecular genetics of achromatopsia
Achromatopsia is a rare autosomal recessive disorder of the cone photoreceptors. Typical characteristics of affected patients include the inability to distinguish colours, impaired visual acuity, photophobia and nystagmus. The condition is said to be more frequent in the Pingelapese population...
Reliability of Fluorescein Dye Disappearance Test (FDDT)
The authors look at the role of the FDDT in the evaluation of adults with primary acquired nasolacrimal duct obstruction (PANDO) and its correlation with the age and severity of epiphora. They report the results of a prospective cross-sectional comparative...
Erythropoietin in healing corneal epithelial defects in rabbits
Corneal epithelial defects heal slowly in patients with diabetes, limbal stem cell deficiency and severe chemical burns. Erythropoietin is a glycoprotein hormone that promotes red blood cell proliferation and inhibits apoptosis of erythroid progenitors as well as nonhematopoietic cells. In...
Correlation between peak intraocular pressure following water drinking test and pulsed methylprednisolone therapy
Steroids have long been known to cause increased intraocular pressures (IOP) in susceptible patients. Intravenous methylprednisolone is used to treat many rheumatological conditions and one of the risks is raised intraocular pressure. It would be useful to find patients at...
Swept-source OCT for measuring peripheral anterior synechiae
The authors report on a cross-sectional study looking at swept-source optical coherence tomography (SS-OCT) for measuring the area and degree of peripheral anterior synechiae (PAS) in patients with angle closure glaucoma. The SS-OCT is commercially available, has a laser wavelength...
Rebamipide 2% for dry eye
Rebamipide is a quinolinone derivative that has been found to increase mucin production and the number of conjunctival goblet cells. A previous phase two study has shown rebamipide 2% to be better than placebo in improving the ocular surface and...
Moxifloxacin 0.5% for bacterial keratitis
The authors report on the results of a randomised controlled trial comparing commercially available non-preserved moxifloxacin 0.5% vs. a combination of fortified cefazolin 5% and tobramycin 1.3% in the treatment of moderate bacterial keratitis without perforation. Corneal scrapings were collected...
The long-term effects of AREDS on AMD progression
The Age-Related Eye Disease Study (AREDS) was an 11-centre, double-masked, clinical trial that in 2001 found a high-dose of antioxidant vitamins plus zinc was effective in protecting against progression of age-related macular degeneration (AMD) in patients with moderate to high...
