You searched for "proptosis"
Proptosis reduction with teprotumumab versus surgical decompression
This study aims to explore whether fat-to-muscle ratio (FMR) can be used to determine the efficacy of teprotumumab when compared to surgical decompression. Simply put, a high FMR equates to more fat expansion and low FMR equates to more muscle...Unilateral Single Wall Decompression of Thyroid Proptosis Following an Incidental Traumatic Injury
Case report A 69-year-old female with a long history of Grave’s ophthalmopathy was under routine follow-up when it was noted during a clinic visit that the amount of proptosis and lid retraction in her right eye had remarkably reduced. A...EOM enlargement in carotid cavernous fistulas
This study evaluates the radiological patterns of extraocular muscle enlargement and proptosis in carotid cavernous fistulas (CCF). At least one muscle was enlarged in 27.5% of cases. The inferior rectus was most commonly enlarged, followed by the medial rectus. Proptosis...Lateral canthal position after lateral orbitotomy
This is a retrospective photographic study of changes in the lateral canthal position following a lateral orbitotomy performed via a lateral canthotomy and cantholysis of both upper and lower limbs of the lateral canthal tendon. Reconstruction of the lateral canthus...Headaches in ophthalmology (part 1)
Ophthalmologists see a large number of patients with headaches or facial pain in the ophthalmic outpatient clinics or in emergency clinics. Over two articles, I will discuss several causes of headaches, ocular manifestations and proposed management and referral options. It...Take this waltz
My last weekend on-call was the busiest I can remember for a very long time. We were just completely swamped with patients. The weather was not too good that Saturday and it felt like every second inhabitant of our ocean...Globe subluxation subsequent to long-term steroids
Globe subluxation, when the globe equator projects anterior to the orbital rim, is a serious orbital condition commonly associated with thyroid eye disease, floppy eye syndrome or a shallow orbit. The authors present a first case of a spontaneous globe...Cataract in patients with pseudoexfoliation syndrome
1 August 2018
| Kurt Spiteri Cornish
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Cataract and Refractive
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Apoptosis, TUNEL, cataract, lens epithelial cell, pseudoexfoliation syndrome
The authors present a prospective comparative study in 43 patients with (group 1) or without (group 2) pseudoexfoliation (PXF) undergoing cataract surgery. Anterior capsule samples were obtained in all patients and analysed for signs of apoptosis by using special staining...
Effects of orbital decompression
This is a retrospective review of 319 orbital decompression operations in 169 patients (73% female) with thyroid eye disease. Three wall decompressions were performed in 92 eyes, 2-wall in 206 (medial and floor), and a single wall (medial) in 18,...Teprotumumab for chronic TED
3 February 2023
| Hetvi Bhatt
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Oculoplastics, Orbit
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Chronic, proptosis, teprotumumab, thyroid eye disease
This retrospective case series looks at the use of teprotumumab in nine patients with thyroid eye disease (TED) of clinical activity score ≤one and >nine months duration, in an American cohort. Current European guidelines have suggested the use of teprotumumab...
Detecting apoptosis in retinal cells
1 February 2022
| Sofia Rokerya
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Retina / Uvea / Vitreous
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Apoptosis, Glaucoma, Imaging, Neurodegeneration, Retina
This is a review paper in which the authors summarise the transitioning of techniques detecting apoptosis from bench to bedside, along with the future possibilities they encase. Detection of Apoptosis in Retinal Cells (DARC) technology can be used as a...
MicroRNAs in cataract
1 August 2016
| Graham Wallace
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Cataract and Refractive
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Age-related cataract, Lens epithelial cells, Lgr4, MicroRNA let-7b, Ultraviolet irradiation
In an ageing population cataract formation is one of the leading causes of blindness. Cataracts are caused by a failure to clear accumulating aggregated proteins in the lens. MicroRNAs are small non-coding transcripts which bind to specific mRNAs acting at...