You searched for "AMD"

1147 results found

Efficacy and safety of intravitreal aflibercept injection in wet age-related macular degeneration

This is a sub-group study of double masked review of patients randomised to different dosages and treatment frequency compared between aflibercept and ranibizumab treatment. This is to evaluate the efficacy and safety of intravitreal aflibercept (IVT-AFL) in Japanese patients with...

Ginko bilboa extract affects hypoxic retinal pigment epithelial cells

Wet age-related macular degeneration (AMD) is characterised by choroidal neovascular membrane (CNVM) formation. It is thought that localised hypoxia within the retina results in overexpression of growth factors such as vascular endothelial growth factor (VEGF), which induces CNVM formation. VEGF...

Belfast Eye Conference 2024

by Zina Mobarak, FY1 Doctor, Manchester University Foundation Trust, UK. The Belfast Eye conference was held online over two days, aimed at anyone interested in ophthalmology and focused on delivering informative talks from specialists in various ophthalmic specialties and presenting...

A missed intraocular telescope – an opportunity to re-focus the evidence

Intraocular telescopes allow magnification of the image so that it would be projected into a larger area of the macula, this makes the central defect caused by dry age-related macular degeneration (AMD) smaller. The most common approach is a Galilean...

Quality matters in the management of serious eye disorders

The author discusses the first quality standard for serious eye disorders from NICE and takes a look at new care models for enhanced service delivery. Patient backlogs pose risks to patient safety, with research showing that people are losing sight...

Broadening of treatment options for potentially blinding retinal conditions

Rod McNeil provides an update on a promising bispecific antibody recently approved for treatment of neovascular age-related macular degeneration (nAMD) and diabetic macular oedema (DMO) and considers emerging developments in biosimilars to established anti-vascular endothelial growth factor (anti-VEGF) therapies, including...

AI breakthrough brings geographic atrophy treatment a step closer

A team led by Dr Konstantinos Balaskas at Moorfields Eye Hospital Reading Centre has developed a fully automated, deep-learning model (algorithm) that can detect and quantify geographic atrophy using standard optical coherence tomography (OCT) scans.

Macular pigment and dark adaptation in older population with normal maculas

Macular pigment (MP) such as lutein, zeaxanthin and meso-zeaxanthin are highly concentrated in the fovea. They protect the retina from damage of ambient blue light via antioxidant properties. In older eyes with normal healthy retina, macular pigment optical density (MPOD)...

What's trending Jun/Jul 2018

#BusyPhillips #photokeratitis #sunglasses Last time, we were in the throes of the Beast from the East. Here in the UK, it’s been a long winter and cold start to spring. The days are longer now, thanks to British Summer Time,...

Multicentre PCO rates in different brands of monofocal intraocular lenses

This was a longitudinal, retrospective cohort study featuring 47,754 (three years) and 20,763 (five years) eyes with age-related (≥65 year) cataract surgeries between 2010-2013 across seven UK ophthalmology clinics. The three- and five-year incidence of posterior capsular opacification (PCO) and...

Student Ophthalmology Review Day: SORD

by Josephine A Bates, FY2 Doctor, North Devon District Hospital, Barnstaple, UK. Opening its doors to medical students across the country once again, the Royal College of Ophthalmologists hosted the Student Ophthalmology Review Day (SORD) with a fantastic turnout. Dr...

Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease

Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...