You searched for "corneal"
Climatic droplet keratopathy
1 December 2015
| Bheemanagouda Patil
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Cornea / External Eye Disease
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UV-B, ascorbate, environment, human, keratopathy
Climatic droplet keratopathy (CDK) is an acquired and potentially handicapping corneal degenerative disease that is highly prevalent in certain rural communities around the world. It predominantly affects males in their 40’s and is known by many other names such as...
Amnion-assisted conjunctival epithelial redirection (ACER): Enhancing stem cell transplantation treatment of total limbal stem cell deficiency
An exploration of Professor Harminder Dua’s recent work using a technique called amnion-assisted conjunctival epithelial redirection (ACER) to aid the success of conjunctival-limbal grafting procedures. ACER provides a refined way to use amniotic membrane (amnion), such as Omnigen® (NuVision® Biotherapies,...Cornea, 2-Volume Set: Fundamentals, Diagnosis, Management and Surgery of the Cornea and Conjunctiva (4th Edition)
Originally published in 1997 as a comprehensive set of three volumes on cornea and external eye disease, this two volume edition, published at the end of 2016, offers “a complete multimedia resource, in print, online, eBook and video format”. There...Stromal cell alignment in damaged cornea
1 August 2017
| Graham Wallace
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Cornea / External Eye Disease
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Confocal microscopy, Corneal wound healing, Extracellular matrix, SHG imaging
Stromal keratocytes are responsible for wound healing in the cornea following damage. Keratocytes at the site of injury become activated and differentiate to myofibroblasts which secrete extracellular matrix (ECM) to close the wound, a response mediated by transforming growth factor...
The results of the last survey Dec22
1 December 2022
| Amar Alwitry
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Ophthalmology
I am regularly faced with litigation whereby the claimant’s cornea has decompensated after cataract surgery. The procedure may have been complicated but sometimes it is not. The eye may have been high risk, for example, a shallow anterior chamber with...
Cornea teaching techniques: one cornea donor tissue for two purposes
2 February 2024
| Bryher Francis, Shokufeh Tavassoli
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EYE - Cornea
There is a national shortage in the UK in corneal graft material [1,2]. The majority (69%) of corneal transplants in the UK are partial thickness, with 35% being Descemet membrane endothelial keratoplasty (DMEK) [2]. During the preparation of the donor...
Characteristics of limbal lymphatic vasculature on confocal microscopy
4 February 2021
| Siyin Liu
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Cornea / External Eye Disease
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Confocal microscopy, Corneoscleral limbus, Immunofluorescence, Lymphatic vessels
This ex vivo study aims to describe the morphological characteristics of the human limbal lymphatic vasculature using confocal microscopy and immunofluorescence. Twelve corneal specimens are obtained from human donor eyes. These corneal buttons are not suitable for transplantation due to...
Use of orthoK for myopia treatment
1 April 2018
| Fiona Rowe (Prof)
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Paediatric Ophthalmology / Strabismus
This article provides an updated literature review on the orthkeratology effect on myopia progression considering outcome measures, potential effect modifiers, mechanisms and current prescription concerns. The discussion centres on the extent of slowed myopia progression, mechanisms, safety concerns and comparisons...
Complications of limbal stay sutures
3 October 2022
| Fiona Rowe (Prof)
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Paediatric Ophthalmology / Strabismus
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Stay sutures, complications, strabismus surgery
There is limited literature describing complications at the limbal suture site. The authors describe two cases with postoperative complications due to use of intraoperative limbal stay sutures. Each case had strabismus surgery at other centres but with presentation to the...
Cell injection therapy for endothelial failure
This is a prospective observational study involving 11 eyes of 11 patients with pseudophakic endothelial failure who underwent human corneal endothelial cell culture (hCEC) injection therapy for endothelial failure. This study aimed to evaluate the long-term five-year postoperative data for...Resurfacing the ocular surface
1 April 2016
| Harminder Dua (Prof)
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EYE - Cornea
The ocular surface (OS) is an anatomical and functional unit made of the tear film, the conjunctival, limbal and corneal epithelium, the lacrimal, mucous and meibomian glands and the lids and blink reflex. The tear film is composed of a...
LASIK for myopia progression
5 February 2020
| Fiona Rowe (Prof)
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Paediatric Ophthalmology / Strabismus
The authors hypothesise that corneal reshaping with refractive surgery could have an effect on myopic progression similar to that of orthokeratology because it results in changes to the central cornea and not to the peripheral cornea. This was a retrospective...