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Strabismus in thyroid eye disease

Pathogenesis Thyroid eye disease (TED) is an auto-immune condition, in the initial phase there is lymphocytic infiltration and oedema of the extraocular muscles with deposition of glycosaminoglycans and hyaluronic acid and adipogenesis, which can lead to an increase in the...

Getting one’s eye in

Lisette Bijma, Sister in the Eye Emergency Department at John Radcliffe Hospital, explains how COVID-19 provided a ‘baptism by fire’ and enabled fundamental and positive changes to the running of the department. Five years ago, I arrived in the UK,...

Bovine pericardium scleral patch graft associated scleritis: Ahmed valve implant for pupillary block glaucoma

Processed bovine pericardium is a lyophilised collagen sheet used as a surgical armamentarium. It renders the material antigenically inert with minimal inflammation [1]. Sclera patch pericardium graft (Tutopatch) is a collagenous membrane derived from solvent preserved, irradiated bovine pericardium [2]...

Quiz Feb/Mar 2024

History A 21-month-old boy presented to his local ophthalmology department with a left proptotic eye from a growing cystic lesion known to be present from birth. Notes taken on presentation were: Known left microphthalmia with chorio-retinal coloboma, contralateral eye was...

Burnout: ubiquitous and unavoidable?

Meriam Islam reminds us of the importance of ‘putting our oxygen mask on first’ and avoiding burnout while we progress through our careers. Burnout. It’s a term we hear a lot. What does it mean though? According to Merriam Webster,...

Line-up confirmed for Eye News Symposium!

We are delighted to confirm an excellent line-up of speakers and topics for the Eye News Symposium, taking place in Glasgow on Sunday 20 January.

Cavernous sinus syndrome

Anatomically the cavernous sinus is a plexus of multiple veins that are connected and within this plexus there are several important vascular and neurological structures. These include cranial nerves III, IV, V1 (and sometimes V2), VI as well as the...

Incidence and risk factors of ocular hypertension following PPV and SOI

In this prospective, interventional study the authors evaluated the risk factors for elevated intraocular pressure (IOP) after pars plana vitrectomy (PPV) with silicone oil injection (SOI). This study included 254 eyes of 254 patients, with a mean age of 55.33...

Unilateral cataract extraction outcomes in older children compared to two studies with younger cohorts

The authors present a retrospective study of children undergoing cataract surgery between the ages of two and seven-years-old at one centre, over a 24-year period. Data including demographics, ocular history, ophthalmic findings, operative reports, adverse events, and record of re-operations...

Differentiating orbital cellulitis from non-specific orbital inflammation

This is a retrospective study looking at whether common laboratory investigations can help differentiate between orbital cellulitis (OC) and non-specific orbital inflammation (NSOI). NSOI is a diagnosis of exclusion following negative investigations for systemic diseases such as IgG4-related disease, granulomatosis...

Occult spread of squamous cell carcinoma into the orbit

The authors describe two cases that may represent perineural spread of cutaneous squamous cell carcinoma (SCC) into the orbit. Both cases had cutaneous squamous cell carcinomas in the region of the lateral orbital wall (innervated by the zygomatico-temporal nerve) which...

Corporate M&A pace gathers momentum

Intensifying franchise competition, maturing product development pipelines and looming loss of exclusivity spur renewed merger and acquisition (M&A) activity in the ophthalmics sector. Rod McNeil reviews recent deals and related strategic developments. AbbVie to acquire Allergan in $63 billion mega-combination,...