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Outcomes of plaque radiotherapy for retinoblastoma
The study authors evaluate their experience of plaque radiotherapy for retinoblastoma (RB) in 41 eyes of 41 patients that failed intra-arterial chemotherapy (IAC). This was a retrospective review including 21 females and 20 males. Median age was 18 months and...Primary eye health care in low- and middle-income countries
The need for eyecare services in low- and middle-income countries Recent global estimates (2020) suggest that there is more than a three-fold difference in the prevalence of all categories of visual loss (presenting visual acuity <6/12 in the better eye)...
Retrospective review of visual outcomes in Idiopathic intracranial hypertension (IIH)
Idiopathic intracranial hypertension (IIH) is a clinical syndrome characterised by headache and papilloedema that can lead to significant visual morbidity. IIH is diagnosed by the modified Dandy criteria, which include normal neuroimaging and cerebrospinal fluid (CSF) composition, high CSF opening...The paediatric cataract: an overview of the embryology and pathophysiology
In the first of the two articles (see Part 2 here) on paediatric cataracts, Samuel Aryee reviews the aetiology of this condition. Cataracts arise from opacification of the natural transparent lens, which can cause partial or total blindness. Although the...If looks could kill – kohl and the eye
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: If looks could kill – kohl and the eye Human fascination with beautification can be traced...Volunteer abroad: the Khmer Sight Foundation
A team of volunteers describe their experiences of working with the Khmer Sight Foundation in Cambodia. Cambodia has a population of 15 million people, of whom an estimated 300,000 are blind. This figure is increasing by 10,000 each year. Three-quarters...
A prospective trial of adjuvant therapy for high-risk melanoma
Patients diagnosed with iris, ciliary body or choroidal melanoma of high-risk tumour cytogenetics (monosomy 3>/= 20% of cells), were treated with adjuvant low-dose dacarbacine (DTIC) and interferon –alpha-2b (IFNA-2b), following primary treatment (enucleation, brachytherapy or resection). DTIC was given intravenously...
Surgical outcomes of isolated medial rectus palsy
Isolated medial rectus is a rare clinical entity. This prospective study of 32 patients from China showed that this was caused most commonly by iatrogenic injury (43.75%), trauma (37.50%) and congenital (18.75%) causes. An average of 60 ±25 prism dioptres...
Surgery to collapse V exo
This paper describes a case report of an extra-large V pattern measuring >60PD and the surgery required to collapse the pattern. The patient was a female aged 20 years. Angle measurements were 70PD at distance and 75PD at near in...
Therapeutic options for advanced cutaneous basal (BCC) and squamous cell carcinomas (SCC)
This article discusses the use of topical and systemic therapy in the management of advanced periocular tumours. It focuses on those that have gained United States Food and Drug Administration approval; namely imiquimod, vismodegib, sonidegib, pembrolizumab and cemiplimab. Imiquimod is...
EP in a case of abducens nerve palsy
Ecchordosis physaliphora (EP) is a rare non-malignant mass that originates from remains of the notochord and is typically asymptomatic. Symptomatic cases are extremely rare, and the majority are managed by surgical resection. This case study reports a 42-year-old male who...
