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5-FU in cicatricial conjunctivitis

This is a retrospective review of 56 patients with cicatricial conjunctivitis, including 25 eyes that received sub-conjunctival injections of 25-50mg of 5-fluorouracil (5-FU) as part of their treatment. Thirty-seven patients had ocular cicatricial pemphigoid (OCP) and 19 had Stevens-Johnson syndrome...

Amniotic membrane transplantation for SJS/TEN

This is a retrospective study of consecutive patients who underwent amniotic membrane transplantation (AMT) in the acute stage of Stevens-Johnson syndrome (SJS) / toxic epidermal necrolysis (TEN) from Toronto, Canada, between 2009 and 2018 and had more than three months...

Extraocular muscle OCT

The goal was to evaluate the use of the Heidelberg anterior segment optical coherence tomography (AS-OCT) to image extraocular rectus muscle insertions and to expand the use of the AS-OCT to also image vertical rectus muscles. The authors evaluated inter...

Brn3b neuroprotective effect in rat glaucoma model

An adeno-associated virus-directed overexpression of the Brn3b protein in hypothesised to confer neuroprotective effects in this paper. This is ultimately tested in a well-accepted rat glaucoma model (Morrison’s model: saline injection into episcleral veins of rat eyes with a force...

Success rates of primary and revision transcanalicular DCR surgery

Transcanalicular laser DCR is a relatively rare procedure compared to more conventional external or endo-nasal techniques. In this article the authors examine the outcomes of revision surgery following failed transcanalicular diode laser dacryocystorhinostomy (TCDL DCR), comparing a conventional external revision...

Superior oblique posterior tenotomy for orbital fracture strabismus

The use of superior oblique posterior tenotomy (SOPT) is reported as a primary procedure in five patients with orbital blowout fractures. The mean follow-up was 15.2 months (6-20). Two patients required further surgery because of a larger vertical deviation. SOPT...

Will it change management?

Like most doctors I have read and am a fan of Samuel Shem’s House of God, with my favourite Rule being Rule 10: “If you don’t take a temperature you can’t find a fever.” If you don’t intend to treat...

Identifying drugs associated with intraoperative floppy iris syndrome

Before David Chang MD from the University of California found out about intraoperative floppy iris syndrome (IFIS), ophthalmologists were mystified each time they came across cataract surgeries that were characterised by sudden intraoperative iris prolapse and pupil constriction. The biggest...

Do topical steroids improve visual outcome in the treatment of bacterial keratitis?

The use of topical corticosteroids as an adjunctive treatment to antibiotics in the management of bacterial keratitis remains a controversial issue. The results of the Steroids for Corneal Ulcers Trial (SCUT) – a randomised, double-masked, placebo-controlled trial that recruited patients...

Les Misérables

I recently had the signal pleasure of undergoing Part 2 of the FRCOphth exit exam and could not help but wonder at how examiners could on the whole be easily categorised into certain subtypes which readers may find fascinating. This...

The results of the last survey Apr 2020

As ever, I would like to thank all those who participated in the last edition’s survey. A lot of data was generated and I do not intend to go through each individual finding. What is staggering again is the degree...

Urban Changes and Rural Struggles for Ophthalmology in China

China is by far the most populated country in the world, with over 1.3 billion inhabitants. It is also the country with the highest number of blind and visually impaired people. As a developing country, half of China’s population lives...