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Differentiating orbital tumours on MRI
This is a literature review examining the ability of specific MRI modalities to differentiate between benign and malignant tumours of the orbit. The authors identified 29 articles reporting diffusion weighted image (DWI) values and corresponding apparent diffusion coefficients (ADC) for...
Quality of life concerns after uveal melanoma diagnosis
The authors sought to investigate factors associated with Quality Of Life (QOL) after initial diagnosis of uveal melanoma (UM) using prospectively collected data between September 2011-May 2016. They included 201 participants referred for radiotherapy after UM diagnosis by an ophthalmic...
Assaying acetylcholine receptor antibodies in the diagnosis of ocular myasthenia
Myasthenia gravis (MG) is an autoimmune disease that leads to impaired neuromuscular transmission. Solely ocular manifestations of MG (OMG) occur in 15-50% of cases, most frequently in the form of fluctuating ptosis and diplopia. Most cases of OMG convert later...
Can coenzyme Q10 have a protective role in ethambutol-induced retinal ganglion cell toxicity
Tuberculosis (TB) is one of the most prevalent infectious diseases, especially in developing or low- income countries. Ethambutol is a widely used drug to treat TB. Ethambutol can cause visual disturbance including ethambutol toxic optic neuropathy (ETON). ETON is one...
Sensorimotor outcomes following paediatric ocular trauma
A retrospective assessment of sensorimotor outcomes was conducted in paediatric patients after ocular trauma to evaluate potential predictors of poor outcome including time of treatment deprivation, Paediatric Ocular Trauma score (POTS) and patient characteristics. The review was from 2006-2020 and...
Significant associations to presence of significant retinal haemorrhages in suspected child abuse
The authors aimed to extract statistically significant associations between non-ocular clinical and diagnostic imaging findings and the presence of significant retinal haemorrhages, and then develop an evidence-based screening algorithm to determine when to consult an ophthalmologist in suspected child abuse...
Rare presentation of giant cell arteritis in Chinese subjects
Only a few case reports of biopsy-proven GCA (BpGCA)-associated vision loss in Chinese subjects have been published. This paper presents three elderly Chinese subjects with BpGCA who presented with vision loss. A search of the literature was also conducted to...
Comparison of vision screening programmes
The purpose was to examine the treatment that children underwent as a result of being identified with reduced vision at school screening. The level of improvement in vision was identified and the time taken to achieve maximum visual acuity. There...
OCTA and pigment epithelium detachments
Yannuzzi et al. report on their study aiming to evaluate the ability of optical coherence tomography angiography (OCTA) to differentiate vascularised from nonvascularised pigment epithelium detachments (PEDs) using conventional imaging techniques, including fundus fluorescein angiography (FFA) and indocyanine green (ICG),...
Pain control during orbital implant surgery
This is a study based on existing evidence that pre-emptive pain control has advantages over traditional post-surgical analgesia. The authors compared pain scores in three groups of randomly assigned and masked patients all undergoing orbital implant surgery under general anaesthesia...
Effects of ML4 on the eye
Mucolipidosis type IV (ML4) is an autosomal recessive lysosomal storage disease and is caused by variants of the MC0LN1 gene. It often presents in young individuals with eye and ocular adnexa issues. The authors present a case report and literature...
