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World-first artificial intelligence foundation model for eye care to supercharge global efforts to prevent blindness

Researchers at Moorfields Eye Hospital and UCL Institute of Ophthalmology (IoO) have developed an artificial intelligence (AI) system that has the potential to not only identify sight-threatening eye diseases but also predict general health, including heart attacks, stroke and Parkinson’s disease.

A pituitary tumour from 1927

The author shares a clinical case from Edinburgh Royal Infirmary’s archives. It is not often in the course of a clinical career that one gets the opportunity to review a patient who had been treated by a pioneer neurosurgeon some...

The challenge of chorioretinal folds in virtual eye clinics

Chorioretinal or choroidal folds are parallel striations involving the retina, retinal pigment epithelium (RPE), Bruch’s membrane, and inner choroid [1]. They can arise from compressive stress on these layers, and their presence often serves as a diagnostic marker for underlying...

Inferior oblique muscle features

The authors aimed to study and morphometrically define the surgical anatomy of the inferior oblique muscle and its variations, and to outline surgical coordinates to aid location of the inferior oblique origin and nerve supply to the inferior oblique muscle....

Learnings and trends in the management of open-angle and angle-closure glaucoma

To be truly disruptive, newer technologies need to offer a quality of life benefit over medication to a broad population of glaucoma sufferers. Evidence and converging trends in medical and surgical management of glaucoma were explored in counterpoint discussions and...

Initiatives in macular service provision

A report from Monitor in October 2015 identifies good practices that will realise most of the potential productivity gain in elective care available to NHS hospitals. These include: stratifying patients by risk and creating low-complexity pathways for lower-risk patients (tailoring...

Conservative surgical management of optic disc pit maculopathy

Four cases are presented in this case report that illustrates the option of conservative surgical management for optic disc pit complicated by maculopathy (ODP-M). Four men aged 24-67-years-old with no spontaneous resolution of ODP-M for a minimum of three months,...

RTP801 as a neuroprotective and axon regenerative treatment

This paper describes the neuroprotective and axon regenerative effects of siRTP801, which is a translatable small-interfering RNA (siRNA) targeting mTOR negative regulator; RTP801, through in-vivo and in-vitro models. In-vivo studies involved an optic nerve crush rat model with intravitreal injections...

Useful and controversial apps and services

These apps and web services are not specifically ophthalmic but hopefully of interest. Office Lens Delegates take pictures of presentation slides at conferences quite frequently. If this is something you do, have a look at the ‘Office Lens’ app. This...

A Doctors.net.uk app and more security woes

Doctors.net.uk gets a new app The Doctors.net.uk website is well known in the medical community. Its online services started 20 years ago, in 1998! Since then it has retained its core features of providing email accounts and also an online...

Incomplete teprotumumab treatment for thyroid eye disease

This is a multi-centre retrospective analysis of clinical outcomes in patients who were on teprotumumab for thyroid eye disease but had the usual regime of eight infusions, three weeks apart, interrupted due to COVID-19. Manufacturing was suspended between Dec 2020...

Eye disease patients have more opportunity than ever to take part in NHS research studies

A new report highlights how 76% of UK hospitals now offer patients the opportunity to take part in studies of eye disease to improve research and innovation. ‘Ophthalmology research in the UK’s National Health Service: the structure and performance of...