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RTP801 as a neuroprotective and axon regenerative treatment

This paper describes the neuroprotective and axon regenerative effects of siRTP801, which is a translatable small-interfering RNA (siRNA) targeting mTOR negative regulator; RTP801, through in-vivo and in-vitro models. In-vivo studies involved an optic nerve crush rat model with intravitreal injections...

My Top Five: Foundation year 3 jobs for prospective ophthalmology candidates

Ophthalmology specialist training (OST) is a fantastic career option, however, it is also a highly competitive specialty. There was a gradual rise in competition ratios in recent years: 3.24 (2019), 5.73 (2020), and 6.80 (2021) [1]. Many choose to pursue...

My Top Five: Foundation year 3 jobs for prospective ophthalmology candidates

Ophthalmology specialist training (OST) is a fantastic career option, however, it is also a highly competitive specialty. There was a gradual rise in competition ratios in recent years: 3.24 (2019), 5.73 (2020), and 6.80 (2021) [1]. Many choose to pursue...

How to get the most out of your ophthalmology elective

If you are in your penultimate year (or even earlier) and have already decided that you want to do ophthalmology, good for you! Ophthalmology is one of the most competitive specialties, and one of the easiest ways to demonstrate your...

Feb/Mar 2018 Quiz

History A 48-year-old farmer with gradual worsening vision in her only eye was referred by her optician. She had recently moved to the UK and required an interpreter during consultation. She seemed to have had vision problems since childhood. Although...

Treatment of diabetic macular oedema

Diabetic macular oedema (DMO) is a common complication associated with diabetic retinopathy, and the most common cause of visual impairment in diabetes [1]. With predicted rising levels of diabetes (in England by 2025 the estimated population with diabetes will be...

Doctor by the sea (Pete’s Hidden Curriculum Part 1)

See Pete's Hidden Curriculum Part 2 here. “They can always hurt you more.” This is The Fat Man’s Law Number 8 from the book The House of God by Samuel Shem. For those that have not read this book, it...

Establishing an intra-arterial chemotherapy service for children with retinoblastoma in Nigeria for the first time

This is the first in a series of three articles (see Part 2 here) about strengthening eye health services in Nigeria through collaboration with the LINKS and Networks run at the International Centre for Eye Health, London School of Hygiene...

Understanding retinal ciliopathy through Bardet-Biedl syndrome

This is a review article looking at up-to-date understanding and ongoing research in retinal ciliopathies. Syndromic ciliopathies consist of a group of disorders caused by ciliary dysfunction or abnormal ciliogenesis. These disorders have multiorgan involvement in addition to retinal degeneration...

Using OneNote in teams

Much like Outlook, Word, PowerPoint and Excel, OneNote is part of Microsoft Office. For this reason it is likely that you will have access to it in your work environment. Used in isolation it is an easy to use and...

A day in the life of...an ophthalmic imager / an orthoptic assistant

The ophthalmic imager My role as an ophthalmic / medical photographer has evolved, dramatically, since I began my career at Manchester Royal Eye Hospital, 30 years ago. Long gone are the days of developing and hand printing fluorescein angiograms in...

Corneal crosslinking in pellucid marginal degeneration

Fourteen studies were included in this first review examining the use of corneal-crosslinking (CXL) to treat pellucid marginal degeneration (PMD). PMD is a bilateral, non-inflammatory corneal thinning disorder characterised by inferior peripheral corneal thinning 1-3mm from the limbus in the...