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Acute comitant esotropia as the presenting sign of diffuse intrinsic pontine glioma

The authors present four children with acute comitant esotropia (AACE) associated with diffuse intrinsic pontine glioma. All were treated with radiation therapy and all subsequently died due to the tumour. Children were aged 5, 5, 4.5 and 11 years. General...

Differentiating orbital cellulitis from non-specific orbital inflammation

This is a retrospective study looking at whether common laboratory investigations can help differentiate between orbital cellulitis (OC) and non-specific orbital inflammation (NSOI). NSOI is a diagnosis of exclusion following negative investigations for systemic diseases such as IgG4-related disease, granulomatosis...

Changes in the choroid after atropine for amblyopic and fellow eyes

The purpose of this study was to compare the effects of atropine on the thickness and structure of the choroid between amblyopic and fellow eyes. This study included 16 patients: five males, 11 females. Median age at ocular coherence tomography...

Issues relating to declining numbers of paediatric ophthalmologists

The authors consider the economic decline of paediatric ophthalmology with a discussion of declining interest among medical graduates and in paediatric ophthalmology fellow numbers. Consideration is given to workforce issues in relation to poor revenue and an increase in the...

Ophthalmic presentations and outcomes in Erdheim-Chester disease

This is a comprehensive article describing clinical manifestations and pathogenesis of Erdheim-Chester disease (ECD) followed by a literature review of the available treatments. The authors look to compare historical treatment (HT) with vemurafenib, a BRAF inhibitor. ECD is a non-Langerhans...

Surgery for third nerve palsy

The authors aimed to evaluate the results of a modified surgical method in patients with chronic total third nerve palsy: superior and inferior halves of the split lateral rectus muscle were passed under the superior and inferior rectus muscles and...

Surgery for horizontal nystagmus

The authors report two consecutive interventional surgical series in which the authors describe their experience with the Sinskey anterior extirpation procedure (SAEP) and a newly modified myectomy without reattachment (MWR). In a review of 39 patients, 20 underwent the SAEP...

Eyelid nodule outcomes

Idiopathic facial aseptic granuloma (IFAG) is a recently defined paediatric dermatology disorder. This study presents the clinical outcomes of children with IFAG nodules on their eyelids with or without facial nodules and aim to compare the outcomes with those presenting...

How many injections in nAMD: ranibizumab vs. aflibercept

Intravitreal anti-VEGF injections make up a large proportion of the workload in ophthalmology clinics. Since the introduction of aflibercept with eight weekly injections there has been an option to use a treatment which may require less treatment, with potential cost...

Vitrectomy after ocriplasmin for VVMT adhesion of MH study

This is a multicentre retrospective study of 51 eyes that received intravitreal ocriplasmin between January 2013 to January 2014 for symptomatic vitreomacular (VMT) +/- macular hole (MH), and then went on to PPV for persistent pathology, comparing a control group...

Treat and extend for PCV

This South Korean study investigated the efficacy of a treat and extend regimen (TER) using ranibizumab to treat polypoidal choroidal vasculopathy (PCV). Twenty-nine eyes were included in this retrospective case note review. Of these, five eyes had been treated with...

Conjunctival mapping biopsies in sebaceous carcinoma

This is a retrospective review of conjunctival mapping biopsies in patients with periocular sebaceous cell carcinoma. The authors reviewed the biopsy technique and outcomes of 45 patients who had mapping biopsies performed over a 25-year period. A total of 429...