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100 years of insulin

*Joint first authors The centenary of the discovery of insulin is a time to celebrate one of the most significant scientific discoveries of the 20th century. Background Before 1923, Type 1 diabetes mellitus [T1DM] resulted in death from severe ketoacidosis...

Artificial intelligence in eyecare: how do we ensure new technologies truly benefit our patients?

From monitoring patients with heart disease to improving the early diagnosis of cancer, artificial intelligence (AI) using deep learning techniques is already employed in many different healthcare specialties [1]. In the eyecare field, AI technologies have been used to analyse...

The happiness coefficient: Pete’s hidden curriculum Part 5

Jeremy: Come on, man, shake your booty! Tonight even Paxman’s out, hoovering up lines of crank off Krishnan Guru-Murthy. Tonight’s the big one.Mark: Jeremy, all rational people agree it’s a truth self-evident that it’s impossible to have a good time...

Investigating the link between corneal clarity and statin use

Transparency is a vital attribute of the cornea, necessary in preserving healthy vision. Maintaining this requires the collective input of the various layers of the cornea. Mostly, the layers implicated in this are the corneal stroma and endothelium [1]. Our...

Primary eye health care in low- and middle-income countries

The need for eyecare services in low- and middle-income countries Recent global estimates (2020) suggest that there is more than a three-fold difference in the prevalence of all categories of visual loss (presenting visual acuity <6/12 in the better eye)...

Retinal prosthetics: science fiction or a vision for the future?

“Is it a fact – or have I dreamt it – that, by means of electricity, the world of matter has become a great nerve, vibrating thousands of miles in a breathless point of time?” – Nathaniel Hawthorne, The House...

Quiz Feb/Mar 2020

History A 92-year-old female patient was referred for a three-month history of a left conjunctival growth with ocular irritation. Her past medical history included: hypertension, back pain and osteoarthritis, all of which were controlled by medication. On examination: vision in...

Aug/Sep 2019 Quiz

History A 73-year-old female patient was referred for rapid growth of two new lesions on the face. She had past medical history of systemic lymphoma. On examination, there was a palpable mass over the left superior orbital region and the...

Dec/Jan 2017 Quiz

History An 18-month-old boy presented with a slow growing left anterior orbital lump medially. Examination revealed a palpable mass beneath the skin at the inferonasal aspect without any visual impairment. A CT scan (Figure 1) followed by an excisional biopsy...

Dec/Jan 2016 Quiz

History A 40-year-old swimming instructor undergoes an enucleation for a blind painful eye. There is a history of soft contact lens wear. She has had a corneal abscess and corneal graft procedures in the past. Questions 1. What does this...

Oct/Nov 2015 Quiz

History A 16-year-old female presents with bilateral ocular irritation. The patient has a history of seasonal rhinitis and eczema and complains of itchy eyes, especially during the summer months. Examination shows bilateral mucoid discharge, conjunctival injection and eversion of both...

Jun/Jul 2015 Quiz

History A 35-year-old male presents with bilateral corneal opacities. Examination shows a honeycomb-type dystrophy. A penetrating keratoplasty is performed and the specimen sent for ophthalmic histopathological assessment. Figure 1 is the haemotoxylin & eosin (H&E). Figure 2 is a Masson...