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Current concepts of the uveitis-glaucoma-hyphaema (UGH) syndrome

4 December 2023 | | Cornea / External Eye Disease | Uveitis-glaucoma-hyphema syndrome, cataract surgery, cystoid macular edema, secondary IOL, vitreous hemorrhage
The authors discuss pathophysiology, aetiology and current management strategies of UGH syndrome. The clinical features of UGH are different than initial descriptions. UGH today is most often associated with posterior chamber IOLs that are not placed within the capsular bag...

Cataract surgery and long-term risk of glaucoma in PEX

1 August 2016 | | Glaucoma | IOP spike, cataract surgery, glaucoma, glaucoma incidence, intraocular pressure, pseudoexfoliation
The objective of this study was to compare the development of glaucoma and IOP over an extended time period following cataract surgery in eyes with and without pseudoexfoliation syndrome (PEX), and trying to determine the impact of cataract surgery on...
Journal of Neuro-Ophthalmology cover image.

A review of the risk of nonarteritic anterior ischaemic optic neuropathy post-cataract surgery

2 February 2024 | | Neuro-Ophthalmology
A systematic review and meta-analysis are presented with the aim of assessing whether cataract surgery increases the risk of non-arteritic anterior ischaemic optic neuropathy (NAION) and identify potential predictors of risk. The search strategy components are outlined in detail. A...

Non-contact-lens-associated acanthamoeba keratitis

1 October 2015 | | Cornea / External Eye Disease | Acanthamoeba keratitis, microbial keratitis, microscopy, non-contact-lens, time of presentation
This retrospective study was done to study the clinical presentation and microbiological results of non-contact-lens-related acanthamoeba keratitis (AK). One hundred and ninety-four patients with microbiological / histopathological diagnosis of AK over four years were included. All patients had corneal scrapings...

Intravitreal injection related endophthalmitis

1 April 2015 | | Retina / Uvea / Vitreous | Age-related macular degeneration (AMD), endophthalmitis, intravitreal injection, post-injection complications, vascular endothelial growth factor (VEGF)
This article reviews the incidence, clinical findings, risk factors, management and visual outcomes in intravitreal injection related endophthalmitis. Incidence of this complication is reported to be in the range of 0.038% to 0.065% (1 in 2000-3000 injections). Patients present typically...

Antibiotic prophylaxis after intravitreal injections

1 June 2014 | | Ophthalmology
The use of topical antibiotics as prophylaxis after intravitreal injections is a contentious issue, especially now with increasing use of intravitreal anti-VEGF agents. In the Wills Eye Institute, prior to May 2011, all patients undergoing intravitreal injections in the office...

Typical and atypical optic neuritis – diagnosis and initial management

1 June 2016 | | Neuro-Ophthalmology
Optic neuritis is a relatively common presentation to ophthalmologists in the acute setting. The vast majority are cases of ‘typical’ optic neuritis (ON) but a smaller group of conditions, so-called, ‘atypical’ optic neuritides require a different work-up and management strategy....

Lessons from an unusual case of syphilis

3 August 2023 | | Retina / Uvea / Vitreous
The rise of syphilis transmission rates over the past two decades has been one of public health’s great puzzles. In the UK, the situation has reached epidemic levels, with a 126% increase between 2013 and 2018 [1]. We present a...

SOS (Simplified Ophthalmic Statistics) Part 3: Which statistical test should I use (if any)?

4 December 2018 | | Ophthalmology
P<0.05 is a statement that brings joy to many researchers. Arguably this is because inclusion of such a statement may increase the chance of acceptance for publication. Whilst statisticians and non-statisticians are united in trying to change this culture, cultural...

Time is vision in central retinal artery occlusion

4 August 2021 | | Ophthalmology, Retina / Uvea / Vitreous, Emergency Ophthalmology
Central retinal artery occlusion (CRAO) is a rare but devastating vascular episode that can have severe impact on vision. Treatment is very time-limited and needs to be initiated very quickly to salvage any vision. The majority of patients present to...

Pituitary tumours: why are they so often missed?

1 April 2017 | | Neuro-Ophthalmology
Part 1: Introduction, historical background and Edinburgh connections (see also Part 2 and Part 3) Is there any ophthalmologist who has not missed a pituitary tumour? Hopefully this article will help those currently in practice to avoid such an embarrassment,...

Don’t ignore the black lesion! It might be mucormycosis

1 June 2017 | | Cornea / External Eye Disease
Keeping mucormycosis infection in the foreground of your differential diagnosis, especially in those more vulnerable patients, will help save their lives if recognised and managed appropriately. Mucormycosis is a fulminant infection caused by the fungi of the family Mucoraceae. It...