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Diagnostic procedures in vitreoretinal lymphoma.

1 December 2014 | | Retina / Uvea / Vitreous | Biopsy, diagnosis, masquerade, vitrectomy, vitreoretinal lymphoma
This paper presented a retrospective review of medical records of HIV negative immunocompetent patients diagnosed with vitreoretinal lymphoma between 1994 and 2012. The aim of the paper was to evaluate the type and number of diagnostic interventions required to confirm...

MicroRNA mediate retinoblastoma signal transduction

1 October 2014 | | Retina / Uvea / Vitreous | KEGG, cell migration, colony formation, microRNA-21, phosphorylation signaling pathway, retinoblastoma, seed-targeting, tiny anti-miRNA
MicroRNAs (miR) are small non-coding single-stranded RNA molecules, normally 22 nucleotides long. There is a large family of miR that control protein expression by binding to mRNAs, leading to their degradation. One important role of miR is in tumours where...

Autophagy in lens mitochondria loss

1 April 2014 | | Cataract and Refractive | ATG5, FYCO1, FYVE and coiled coil domain containing 1, LC3B, OFZ, Pik3c3, TOM20, autophagy, autophagy-related 5, cataract, differentiation, electron microscopy, lens, microtubule-associated protein 1 light chain 3B, mitophagy, organelle free zone, phosphatidylinositol 3-kinase, catalytic subunit type 3, translocase of the outer mitochondrial membranes 20 kDa
The lens consists of a monolayer of epithelial cells that overlies fibre cells that differentiate from epithelial cells at the equator. While developing, fibre cells need mitochondria to provide energy, as they mature they lose these and other organelles to...

A case report of cavernous sinus syndrome following dental procedure

1 April 2014 | | Neuro-Ophthalmology
This case report describes a patient presenting with painful diplopia as a consequence of root canal dental treatment. Following root canal treatment a non-resolving tooth pain led to a decision to extract the tooth, leading to onset of severe periorbital...

Do topical steroids improve visual outcome in the treatment of bacterial keratitis?

1 December 2014 | | Cornea / External Eye Disease
The use of topical corticosteroids as an adjunctive treatment to antibiotics in the management of bacterial keratitis remains a controversial issue. The results of the Steroids for Corneal Ulcers Trial (SCUT) – a randomised, double-masked, placebo-controlled trial that recruited patients...

Identifying drugs associated with intraoperative floppy iris syndrome

1 April 2016 | | Cataract and Refractive
Before David Chang MD from the University of California found out about intraoperative floppy iris syndrome (IFIS), ophthalmologists were mystified each time they came across cataract surgeries that were characterised by sudden intraoperative iris prolapse and pupil constriction. The biggest...

The results of the last survey Apr 2020

1 April 2020 | | Ophthalmology, Cataract and Refractive
As ever, I would like to thank all those who participated in the last edition’s survey. A lot of data was generated and I do not intend to go through each individual finding. What is staggering again is the degree...

Les Misérables

1 October 2014 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
I recently had the signal pleasure of undergoing Part 2 of the FRCOphth exit exam and could not help but wonder at how examiners could on the whole be easily categorised into certain subtypes which readers may find fascinating. This...

Urban Changes and Rural Struggles for Ophthalmology in China

1 December 2013 |
China is by far the most populated country in the world, with over 1.3 billion inhabitants. It is also the country with the highest number of blind and visually impaired people. As a developing country, half of China’s population lives...

Aniridia Network 2023 Conference: Amy's experience as a first-time attendee

6 October 2023 | | aniridia, patient perspective, amy woodward
I have lived with aniridia since birth; and no matter how many specialised doctors you see or how many other people with visual impairments you meet, you still feel isolated, different and misunderstood. This is the exact reason Aniridia Network is important.

RNIB makes sound decision to create memorable new sonic logo

6 December 2023 | RNIB, Sonic, Branding, sight loss, sight impairment, blind
Leading sight loss charity RNIB (Royal National Institute of Blind People) turned to blind and partially sighted people to help create a new sonic identity for the charity.

RNIB Connect Radio wins prestigious gold ARIAS award

28 May 2024 | radio, awards, RNIB, Indutry, charity
A Glasgow-based radio station has won a 2024 Audio and Radio Industry Awards (ARIAS) for Community Station of the Year. RNIB Connect Radio was established by leading sight loss charity RNIB to provide news, information and entertainment to blind and partially sighted people across the UK.