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Sickle cell eye disease: an overview of vitreoretinal complications and their surgical management
Sickle cell disease is the most common genetic disorder worldwide and is associated with lifelong anaemia, intermittent pain and multi-organ morbidity. Ocular involvement can be associated with significant visual impairment due to the complications of proliferative sickle retinopathy (PSR). Occasionally...CALL TO ACTION: Help the Ridley Eye Foundation ‘reach more of the unreachable’ in the Himalayas
On the 29 November 1949, Harold Ridley carried out the first implant of an intraocular lens (IoL). This was the first major breakthrough in the cure of cataract blindness since Jacques Daviel conducted the first extra-capsular extraction 198 years earlier....LSHTM: Skills for Eye Field Research
This course takes place in November/December each year on Thursdays and Fridays over 3 weeks (5 teaching days and one day for the written assessment). All sessions are delivered face-to-face for the whole day (09:30 - 12:45 and 14:00 -...
Topical atorvastatin for dry eye and blepharitis
Dry eye is a very common problem with 20% of the population affected and is frequently associated with blepharitis (DEB), which has an over prevalence of about 40%. The aim of this study was to evaluate a topical atorvastatin formulation...
Cytotoxic effect of voriconazole on human corneal epithelial cells
Voriconazole is a second-generation synthetic derivative of fluconazole with broadened antifungal spectrum. It is becoming the drug of choice for fungal keratitis. Voriconazole eye drops are not available commercially, thus have to be prepared by diluting the intravenous formulation containing...A personal reflection: working at the International Centre for Eye Health from 2006–2024
I feel incredibly fortunate to have been working part-time at the International Centre for Eye Health (ICEH) [1] since 2006. Earlier in my career, the responsibilities of work and a growing family made this merely an aspiration, and apart from...
Prediction errors of formulas in optical biometers
This study was conducted retrospectively in a private practice setting. Nine formulas were compared for prediction error (postoperative spherical equivalent (SE) minus, predicted SE calculated by each formula), using two optical biometers (Lenstar – optical low coherence reflectometry (OLCR) and...Optimising an acute eye service in the current COVID-19 crisis
With the current global pandemic of COVID-19 we have all had to redesign and reorganise our normal working practices. Non-urgent hospital work has been postponed to allow redistribution of resources, redeployment of hospital staff and to reduce the risk of...Turn up anytime
When I was starting off in ophthalmology my then boss had a standard spiel after completing a cataract case. It did not vary and I do not recall an instance of it not taking place. “The operation went well and...
Choroidal thickness in ocular sarcoidosis by OCT measurement
This is the first study to evaluate the choroidal thickness in patients with ocular sarcoidosis during the quiescent phase using enhanced depth imaging optical coherence tomography (EDI-OCT) and comparing with normal subjects. Ocular sarcoidosis may affect the choroidal circulation (occlusive...
Effects of blood donation on the physiology of the eye
Hypovolaemia is a state of decreased blood volume, the reduction of which reduces tissue perfusion which may in turn lead to cellular hypoxia and end-organ damage. In blood donation, 500ml of blood is collected in ten minutes. This equates to...
