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Aflibercept for the treatment of neovascular glaucoma
The aim of this study was to investigate initial results regarding the treatment of neovascular glaucoma (NVG) with intravitreal aflibercept. NVG is classified into stages 0-3. In stages 1 and 2, abnormal vessel proliferation is seen with or without elevated...
Syndromic V-pattern management
The authors document their experience in the management of four cases of Crouzon syndrome and review the anatomical extraocular muscle anomalies noted during surgery. Horizontal strabismus surgery varied in each of the four cases according to individual extraocular muscle abnormalities...
Surgical complications of ReLEx
Femtosecond laser refractive lenticule extraction (ReLEx) is a novel procedure for treatment of myopia and myopic astigmatism, which eliminates the use of microkeratome and excimer laser. Currently there are two techniques: FLEx – femtosecond lenticule extraction (similar to conventional LASIK)...
RPTP-σ increases pro-MMP activity in a trabecular meshwork cell line following oxidative stress conditions
This study aims to outline the role of phosphatases in the aqueous drainage system by overexpressing receptor tyrosine phosphatase sigma (RPTP-σ) in a human normal trabecular meshwork cell line and describing its effect on subtypes of matrix metalloproteinases (MMP) and...
Systemic anti-inflammatory versus fluocinolone acetonide intraocular implant
In the Multicenter Uveitis Steroid Treatment (MUST) trial, 255 patients with intermediate uveitis, posterior uveitis or panuveitis were randomised to either fluocinolone acetonide intraocular implant or systemic corticosteroid therapy which was supplemented with immunosuppression if required. Patients were followed up...
Ozurdex wound leakage
This letter to the editor describes two cases of wound leakage after Ozurdex injection. The first case is a man who had four previous injections for an underlying diagnosis of chronic serpiginous choroiditis, who was also on a course of...
PD-1 and retinal ganglion cell death
Death of retinal ganglion cells (RGC) in conditions like glaucoma leads to permanent visual loss. RGC death can be due to the initial stress such as raised intraocular pressure or secondary to mechanism such as oxidative stress. Programmed cell death-1...
Early diagnosis of pituitary apoplexy using combined MRI findings
The author presents a literature review searching the terms ‘pituitary ring sign’ and ‘sphenoid sinus mucosal thickening’ in the context of pituitary apoplexy from 1990 until the present day. These two findings are both magnetic resonance imaging (MRI) signs of...
Effectiveness and Safety of Dexamethasone implants for post surgical macular oedema including Irvine-gass syndrome
This is a retrospective, multicentre, uncontrolled, consecutive case series from Lyon, France between April 20111 to June 2014, with minimum of one year follow-up. The clinical features including the best corrected acuity (BCVA), central subfield macular thickness (CSMT) and intraocular...
Intravitreal aflibercept for diabetic macular oedema
The VISTA and VIVID randomised phase 3 trial were designed to compare the efficacy and safety of intravitreal aflibercept injections versus laser photocoagulation for diabetic macular oedema (DMO). A total of 872 patients with centrally involving DMO were recruited, and...
Amblyopic choroidal thickness
The authors studied choroidal thickness in 38 paediatric cases (76 eyes) with unilateral amblyopia to evaluate the differences between amblyopic and fellow eyes, and compare them with 19 healthy control subjects (38 eyes). Anisometropic amblyopia was present in 17 cases...
