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The Eye in History

Amongst the numerous texts that are available, one occasionally encounters a history of ophthalmology. There is such rapid development of technology in recent years and one can get drawn into the minutiae of a particular subject, losing track of the...

Retinal vascular occlusion from gentamicin injection post-vitrectomy

The authors present two case reports for the rare, but serious, complication of retinal vascular occlusion as a presumed result of subconjunctival injection following 25-gauge vitrectomy. Risk factors for the complication include: cardiovascular disease, retrobulbar anaesthesia, high intraocular pressure (IOP)...

Reflections of a Pupil: What Your Med School and Ophthalmology Textbooks Can’t Teach You (But What Your Mentors, Colleagues and Patients Will)

Reflections of a Pupil is a thought-provoking collection of anecdotes, clinical pearls and life lessons written by Ophthalmologist R Rishi Gupta. While ophthalmologists have a seemingly endless collection of textbooks to choose from to build their knowledge, this book offers...

Aflibercept treatment in polypoidal choroidal vasculopathy

The authors present a study to evaluate the anatomical and functional efficacy of aflibercept intravitreal (IVT) as a monotherapy in polypoidal choroidal vasculopathy (PCV) in a Caucasian population treated with initial three-monthly aflibercept IVT, followed by a bimonthly regimen for...

Congenital dacryocystocele in UK

The authors report the first national study of dacryocystocoeles in UK. They report an incidence of one in 18,597 live births in the UK for congenital dacryocystocele. A prospective observational study of 49 cases of congenital dacryocystocele presenting between September...

Intravitreal bevacizumab vs. ranibizumab in the treatment of macular oedema due to BRVO

This is a randomised, prospective, non-inferiority trial of 75 patients with macular oedema due to a branch retinal vein occlusion (BRVO) who received intravitreal injections of ranibizumab or bevacizumab after 1:1 block randomisation. This study is to measure the difference...

Cataract surgery in small adult eyes

This is a retrospective audit of a five year study period, between the periods of January 2006 to December 2010, where a surgical log book search was performed. The inclusion criteria of this study were intraocular lenses (IOL) power greater...

Rebamipide 2% for dry eye

Rebamipide is a quinolinone derivative that has been found to increase mucin production and the number of conjunctival goblet cells. A previous phase two study has shown rebamipide 2% to be better than placebo in improving the ocular surface and...

More sensitive visual acuity test for age-related macular degeneration

Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world. Primarily associated with ageing, genetic factors and lifestyle choices such as smoking also play a contributory role. Patients with early AMD, characterised by the development of...

White dot syndromes

It is fair to say that trainees and consultants who are not medical retina specialists are a bit scared of the so called retinal ‘white dot syndromes’. It is easy to understand why this is the case, as almost every...

Stem cell therapy for Parkinson’s disease: researching for an 
effective cure

Neurodegenerative diseases are characterised by the chronic and progressive loss of neurons, which in turn results in loss of cognitive and physical functions. The World Health Organization has estimated that the disability-adjusted life years lost from neurological disease was about...

Good news: new study links moderate wine consumption to lower risk of cataract surgery

An observational study published today in Ophthalmology (the journal of the American Academy of Ophthalmology) indicates that low to moderate alcohol consumption is associated with a lower risk of requiring surgery for cataracts, although the nature of the study means it does not definitively prove a direct causal effect.