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Eye Capacity: clinical need should drive ophthalmic service provision

1 February 2014 |
Almost two million people in the UK suffer sight loss, a number forecast to double over coming decades. Major causes of blindness are age-related macular degeneration (AMD), glaucoma, diabetic retinopathy, cataract and uncorrected refractive error. Prevalence of these sight-threatening conditions...

AI breakthrough brings geographic atrophy treatment a step closer

20 September 2021
A team led by Dr Konstantinos Balaskas at Moorfields Eye Hospital Reading Centre has developed a fully automated, deep-learning model (algorithm) that can detect and quantify geographic atrophy using standard optical coherence tomography (OCT) scans.

Macular pigment and dark adaptation in older population with normal maculas

1 December 2018 | | Retina / Uvea / Vitreous | Macular pigment, Müller cells, aging, dark adaptation
Macular pigment (MP) such as lutein, zeaxanthin and meso-zeaxanthin are highly concentrated in the fovea. They protect the retina from damage of ambient blue light via antioxidant properties. In older eyes with normal healthy retina, macular pigment optical density (MPOD)...

Brolucizumab in age-related macular degeneration, HAWK Study

3 October 2023 | | Retina / Uvea / Vitreous | Neovascular age-related macular degeneration, aflibercept, anti-vascular endothelial growth factor therapy, brolucizumab, commercial formulation
The aim of the study was to collect additional data on efficacy and safety of brolucizumab 6mg intended for commercialization in age-related macular degeneration (AMD) (with an increase in pH and decrease in polysorbate concentration). The HAWK Study was a...

How many injections in nAMD: ranibizumab vs. aflibercept

1 April 2017 | | Retina / Uvea / Vitreous | aflibercept, clinical practice, neovascular age-related macular degeneration, ranibizumab, visual acuity
Intravitreal anti-VEGF injections make up a large proportion of the workload in ophthalmology clinics. Since the introduction of aflibercept with eight weekly injections there has been an option to use a treatment which may require less treatment, with potential cost...
British Journal of Ophthalmology cover image

Ocular adnexal marginal zone b-cell lymphoma

5 August 2020 | | Ocular Pathology and Oncology | conjunctiva, epidemiology, eye lids, neoplasia, orbit
This is a multicentre retrospective study of seven eye centres of 689 patients with ocular adnexal extranodal marginal zone b-cell lymphoma (OA-EMZL). The median follow-up time was 42 months and the median age was 62 years. Fifty-five percent were women;...

Sharing best practice and landmark evidence in glaucoma care

1 August 2019 | | Ophthalmology, Glaucoma
Evolving technology, best practice and landmark evidence in glaucoma care were reviewed by an international expert faculty in session presentations and debates during the 11th Moorfields International Glaucoma Symposium 2019. The authors were meeting chairs and provide an overview of...

What's trending Oct/Nov 2019

1 October 2019 | | Emergency Ophthalmology, Ophthalmology, Retina / Uvea / Vitreous
#probeyeotic #eyeballbugs #microbiome The human microbiome usually conjures up images of the gastrointestinal tract and yoghurt containing good bacteria. However, research suggests that the ocular mucosa is home to a unique microbe collection, with important immunological functional properties [1]. This...

Update on emerging therapies for age-related macular degeneration

4 December 2023 | | AMD
The 23rd European Society of Retina Specialists (EURETINA) Congress, held in Amsterdam, the Netherlands, provided a timely update on anti-complement therapy for geographic atrophy and emerging investigational therapies for neovascular age-related macular degeneration. Anti-complement therapy for geographic atrophy Geographic atrophy...

What's trending Dec/Jan 2020

2 December 2019 | | Ophthalmology, Retina / Uvea / Vitreous, Cataract and Refractive
#eyedoctor #banned #visamix-up #HomeOffice #hostileenvironment An ophthalmologist was left stranded overseas when the Home Office refused him entry due to a visa mix-up. Dr Chan was working as a fellow at Moorfields Eye Hospital until August 2019, then was offered...

Leadership skills training through the COECSA-RCOphth LINK

1 June 2017 | | Cataract and Refractive, Cornea / External Eye Disease, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous, AMD, Emergency Ophthalmology
The Lead Forward project was an initiative of the VISION 2020 LINKS Programme, funded by the Department for International Development (DFID) via the Tropical Health Education Trust (THET). It aimed to improve the quality of medical leadership within VISION 2020...

Intravitreal injections delivered by ophthalmic clinical nurse specialists

1 June 2015 | | Retina / Uvea / Vitreous
Intravitreal injections of the anti-vascular endothelial growth factor (anti-VEGF) agent ranibizumab, for the treatment of wet age-related macular degeneration (AMD) was approved by National Institute for Health & Care Excellence (NICE) in 2008 [1]. The Manchester Royal Eye Hospital (MREH),...