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Complex Biometry Clinics: a new service development
In this article we describe a new local service development, the ‘Complex Biometry Clinic’ at Leicester Royal Infirmary. Retrospective data analysis of patients referred between October 2012 and October 2013 was performed. The aim was to provide a one-stop service...Exploiting nature’s randomised trials of eye disease
Confounding and reverse causation in observational ophthalmic epidemiology Traditional observational studies are inherently limited in establishing a causal effect of an exposure on an outcome of interest. One fundamental limitation is confounding, whereby causation is incorrectly attributed to a third...
Micropulse vs. continuous wave trans scleral diode cyclophotocoagulation in refractory glaucoma
Continuous wave cyclophotocoagulation (CWCPC) delivers continuous high intensity energy to the ciliary body in an attempt to reduce aqueous secretion and hence lower IOP. It is often used as a treatment of last resort due to the potential side-effects of...
Cataract surgery in patients with Vogt-Koyanagi-Harada
This retrospective, interventional case series of 286 patients (408 eyes) assessed visual outcome and prognostic factors in patients with Vogt-Koyanagi-Harada (VKH) undergoing cataract surgery between September 2008 and December 2017. Two groups were reviewed. The first group (352 eyes) had...In conversation with Dr Robert B Nussenblatt
Dr Robert B Nussenblatt is Chief of the Laboratory of Immunology at the National Eye Institute, an eminent ocular immunologist and an expert in clinical research design and conduct. Describe the success or relevance of the SUN project. The Standardization...Retina UK Professionals' Conference 2023
The Retina UK Professionals’ Conference will be held in-person and online on Friday 8 July 2022 and will look at what our community has told us they need in terms of support from the charity and health sectors. You will...
Scleral fixation using Gore-Tex suture of a subluxated PCIOL
This was a retrospective single-centre study of patients who underwent lasso in-the-bag scleral fixation of a subluxated posterior chamber (PC) intraocular lens (IOL) using the snare technique with Gore-Tex suture from 2019 to 2021. Functional outcome was analysed by clinical...Retinoblastoma – the challenges of a rare cancer and the role of international partnerships
Introduction: the global challenge The global burden of retinoblastoma (Rb) is one in 15,000-18,000 live births, which equates to 8000 new cases worldwide each year. The global disparities in Rb outcome represent a paradigm of health inequality worldwide [1]. In...Randomisation, confounding & observational methods in ophthalmic epidemiology
Randomisation and confounding Understanding the relationship between an exposure and an outcome of interest is the central challenge in ophthalmic epidemiology. The exposure may be aetiological, taking the form of a putative risk biological factor, or therapeutic, in the form...
Outcomes of cataract surgery in eyes with weak zonules
Pseudoexfoliation (PEX) and zonular weakness have long been known to increase the risk of complication of cataract surgery. This retrospective study looks at the results of phacoemulsion and intraocular implantation in 295 eyes with pseudoexfoliation and zonular weakness, with a...
PlusoptiX and SPOT screening
The goal of this study was to determine whether an instrument that uses referral criteria having a high specificity (plusoptiX S08) would fail to refer children who have significant amblyopia and who would have been detected by an instrument using...
