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2640 results found

PD-1 and PD-L1 in exenteration specimens

This is an immunohistochemical study looking at variation in the expression of the programmed death-1 receptor (PD-1) and the programmed cell death ligand-1 (PD-L1), comparing cutaneous malignancies which invaded the orbit with uncomplicated nodular basal cell carcinomas. The authors retrospectively...

Computerised tomography in ocular trauma patients

Ocular trauma can be common in military settings. This retrospective study looked into the relationship between the clinical effects of acute ocular and orbital blast trauma with the findings on computerised tomography (CT). This was a consecutive case series of...

A retrospective study of the use of Dermis Fat Grafts for orbital volume augmentation

The authors describe the outcomes of 173 primary Dermis Fat Grafts (DFGs) and 66 secondary DFGs. Median follow-up for the primary group was 21.5 months and 14 months for the secondary group. Outcome measures included: prosthesis motility, prosthesis fit, patient...

All you need to know about PIC

This is a review article of punctate inner chorioretinopathy (PIC). The authors detail the epidemiology and clinic presentation of the disease. They recognise the challenge of an accurate diagnosis due to its resemblance to other posterior uveitic entities. Multimodal imaging...

Part 1: The Arclight Project – Frugal tech for sight

Click here for Part 2 on this topic. The Arclight Project is a mix of frugal design, manufacturing, distribution, teaching, research, and advocacy, all wrapped up in a social enterprise based at the University of St Andrews. The project is...

Well-presented scholarly research work will reduce chances of journal rebuttal

Submitting to an academic journal? Are you aware of the requirements and constraints of relevant copyright laws? Rod McNeil provides a guide for aspiring authors. Getting published in peer-reviewed academic and medical journals is not easy. But careful attention to...

Practical phacodynamics – making the most of your phacoemulsification machine

Understanding phacodynamics is appreciating the subtleties in the dynamic changes of the fluidics and the ultrasonic power delivered. Kristina Southcott explains. Increase my vacuum! Increase my bottle height! Increase my phaco power! I frequently observe the above commands being directed...

Obituary: Sohan Singh Hayreh (1927 - 2022)

Sohan would have been 95 on 6 November this year, but due to complications of COVID-19, he passed away on 29 September.

Screening for Sickle Cell Retinopathy (SCR): Why we do wide-field imaging, OCT/OCT-A for SCR – Newcastle upon Tyne Hospitals NHS Foundation Trust

I have been working in ophthalmology for over five years as a photographer and research co-ordinator, and it is fascinating, rewarding, and interesting to learn all about the different diseases associated with the eye. One condition that has been a...

Pituitary tumours: why are they so often missed?

Part 2: Clinical varieties, anatomical considerations and case report (see also Part 1 and Part 3) For ophthalmologists there are four types of pituitary tumour to be considered, three of which are named according to the hormone secreted, along with...

Treatment for post stroke visual impairment – clinical practice versus literature evidence

The aim of this paper is to compare the treatments reported in a large scale stroke study (Vision in stroke (VIS) Study) against the treatments identified in a full systematic literature review. The purpose was to identify which treatment /...

Understanding retinal ciliopathy through Bardet-Biedl syndrome

This is a review article looking at up-to-date understanding and ongoing research in retinal ciliopathies. Syndromic ciliopathies consist of a group of disorders caused by ciliary dysfunction or abnormal ciliogenesis. These disorders have multiorgan involvement in addition to retinal degeneration...