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2640 results found

Detecting apoptosis in retinal cells

This is a review paper in which the authors summarise the transitioning of techniques detecting apoptosis from bench to bedside, along with the future possibilities they encase. Detection of Apoptosis in Retinal Cells (DARC) technology can be used as a...

Glaucoma patients can monitor and treat their own IOP!

Simerdip Kaur takes a look at the latest ophthalmology-related stories in the news. Headline: Glaucoma patients can monitor and treat their own IOP! It is well known that poorly controlled intraocular pressure (IOP) is a leading risk factor for glaucoma...

Gonioscopy: A Video Assisted Skill Transfer Approach

Gonioscopy is a critical part of the eye examination, a challenging technique to learn and although drawings and photographs are helpful, videos that demonstrate the technique and findings are particularly valuable. Interpretation beyond merely identifying whether there is a closed...

Paraneoplastic optic neuropathy features

This is a retrospective review of seven patients diagnosed with paraneoplastic optic neuropathy (PON) between January 2015 and June 2017. Five patients had a history of primary malignancy, including papillary thyroid carcinoma, type B thymoma, testicular seminoma and lung carcinoma....

Thyroid eye disease and obstructive sleep apnoea

This is a retrospective study looking for an association between compressive optic neuropathy in thyroid eye disease (TED-CON) and obstructive sleep apnoea (OSA). One hundred and nine patients with thyroid eye disease were asked to complete a validated questionnaire designed...

Prognostic factors for visual acuity in patients with LHON after gene therapy

This retrospective study investigates prognostic factors affecting the visual acuity after a single intravitreal injection of rAAV2-ND4 gene therapy in 53 patients with Leber’s hereditary optic neuropathy (LHON) with mutation at site 11 778. Patients were reviewed one and three...

A case study of posterior globe flattening in idiopathic intracranial hypertension

The authors present a single case of posterior globe flattening without papilloedema in idiopathic intracranial hypertension. The case was a 64-year-old woman with a one-year history of transient visual loss in her left eye only. Visual acuity was 20/20 in...

A novel way to distinguish between types of anterior ischaemic optic neuropathy

The authors evaluate the monocyte to high-density lipoprotein (HDL) ratio (MHR) in patients with arteritic and non arteritic anterior ischaemic optic neuropathy (A-AION / NA-AION). A distinction between the two types of AION is essential to begin appropriate treatment, which...

Using MRI to assess normal variation in optic chiasm anatomy

The authors present an MRI study including 61 MRI scans using a 1.5 T with slice thickness of 1 or 5mm and the sequence showing the highest resolution of the chiasm. A predetermined set of measurements were taken in a...

Unusual case presentation of arteritic anterior ischaemic optic neuropathy

The authors present a single case of an 84-year-old man with arteritic anterior ischaemic optic neuropathy, but with unusual features on temporal artery biopsy. He presented with a three-day history of sudden onset of loss of vision in his right...

ROPPVAL Syndrome as a differential diagnosis to optic neuritis

Optic neuritis (ON) is a common cause of visual loss in young patients. Patients with eye pain and ipsilateral visual loss are often referred into neuro-ophthalmology clinics with a possible diagnosis of ON. In 2018 Jefferis et al. reported a...

Case report of Leber hereditary optic neuropathy (LHON)

This case report presents a 74-year-old male patient who developed LHON, with a previous diagnosis of bilateral macular holes. LHON occurs predominantly in healthy young men and onset in older age ranges increases the likelihood that the patient will have...