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Does Acanthamoeba need bacteria to cause keratitis?
An animal study was carried out on 36 rabbits, whose corneas were inoculated with either Acanthamoeba castellanii alone, Pseudomonas aeruginosa alone or both pathogens together after a period of short (two hours) or long (six hours) co-incubation. The clinical severity...
Cytotoxic effect of voriconazole on human corneal epithelial cells
Voriconazole is a second-generation synthetic derivative of fluconazole with broadened antifungal spectrum. It is becoming the drug of choice for fungal keratitis. Voriconazole eye drops are not available commercially, thus have to be prepared by diluting the intravenous formulation containing...
Review of efficacy and safety of tetracaine drops in strabismus surgery
Tetracaine is a topical anaesthetic drug used to anesthetise the eye and surrounding areas during strabismus surgery. It is generally safe and well tolerated but can cause mild adverse reactions at the site of use and, in rare cases, serious...
Corneal suture sample evaluation
This is a prospective study of 35 patients’ suture samples taken from a tertiary cornea clinic, Miami, Florida, with a history of penetrating keratoplasty. The aim is to study the relationship between corneal suture bacteriology, biofilm and the clinical setting,...Thinking outside the box – adapting to the COVID-19 lockdown
How can we avoid further delays to follow-up in glaucoma patients? The author asks if there is a socially distanced way to check IOPs in those at high risk of losing vision. Glaucoma is an asymptomatic condition. Loss of the...Photophobia: an unusual symptom of a pituitary macroadenoma
Introduction Photophobia, defined as ‘an abnormal intolerance to light’, is commonly associated with a range of both ocular and neurological pathologies such as dry eye, blepharospasm, corneal pathologies, cataracts, uveitis, retinal dystrophies, optic neuritis, migraine, meningitis, and traumatic brain injury...
Diabetic polyneuropathy and risk of developing diabetic retinopathy
Diabetic polyneuropathy (DPN), diabetic retinopathy (DR) and diabetic nephropathy are widely classified as microvascular complications of diabetes. DPN, which may cause complete sensation loss, is another common complication of DM. The DPN-related diminished sensation presents a significant risk factor for...
