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Effects of blood donation on the physiology of the eye
Hypovolaemia is a state of decreased blood volume, the reduction of which reduces tissue perfusion which may in turn lead to cellular hypoxia and end-organ damage. In blood donation, 500ml of blood is collected in ten minutes. This equates to...
Is laser refractive surgery safe for patients taking isotretinoin?
This multicentre, retrospective, interventional case series assesses the outcomes of laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) in 113 patients taking isotretinoin between January 2003 and September 2017. Isotretinoin is contraindicated for LASIK and PRK and patients are...
Using a pupillometer to confirm presence of RAPD in post stroke homonymous hemianopia
It has been reported that relative afferent pupillary defects (RAPDs) may be present in patients with occipital lobe lesions. However, a small contralateral RAPD due to a difference in the crossed and uncrossed fibres can be difficult to detect using...Dr Peter Davey joins the SEE Summit
The Association of British Dispensing Opticians (ABDO) has announced another speaker for the SEE Summit, Dr Peter Davey, Chief Sustainability Officer’s Clinical Fellow 2022–2023, working with NHS England on a variety of projects including net zero eyecare.
Brolucizumab in age-related macular degeneration, HAWK Study
The aim of the study was to collect additional data on efficacy and safety of brolucizumab 6mg intended for commercialization in age-related macular degeneration (AMD) (with an increase in pH and decrease in polysorbate concentration). The HAWK Study was a...
Changing operating room practices: the effect on postoperative endophthalmitis rates following cataract surgery
This is a retrospective clinical registry study from India of 85,552 cataract surgery patients; group 1 (56,551 patients from January-March 2020) and group 2 (29,011 patients from May-August 2020). Group 1’s patients were ungowned, surgical gloves were disinfected but not...
Progression of high anisometropia in children
This study aimed to analyse the stability and progression of higher degrees of myopic anisometropic in children. This retrospective study included 63 children meeting the inclusion criteria. Mean age at initial visit was 4.3 years ±2. There were 51% males...
Corneal stroma modelling under hypoxic conditions
The cornea is exposed to hypoxia under several conditions including sleep, inflammation and wound healing. Being an avascular tissue to maintain transparency, how the cornea homeostatic controls oxygen tension is important. To address this process two models were utilised; a...
Effect of intravenous mannitol in post vitrectomised eyes
The purpose of the study was to evaluate the effect of intravenous mannitol 20% on intraocular pressure in vitrectomised silicone-oil filled eyes. A prospective analysis of consecutive patients was undertaken with their fellow eyes taken as controls. Thirty-one patients were...
Binocular summation responses in strabismic amblyopia
A preliminary study was conducted to determine whether binocular summation (BS) in strabismic amblyopia is more decreased than in strabismus alone and whether strabismus surgery improves BS. The study included 15 strabismic amblyopes, 30 normal controls and 30 strabismic controls....
Choroidal thickness in strabismus and amblyopia
The authors examined the effect of exotropia, esotropia, anisometropic amblyopia and hypermetropia on choroidal thickness in a prospective cross section study. The study included 100 patients and 20 controls with a mean age of 8.5±2.9 years; 61 female and 59...
