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Retinoblastoma management update (part 2): treatment, screening and surveillance, long-term follow-up and new developments

1 February 2017 | | Ocular Pathology and Oncology
Retinoblastoma treatment requires significant multidisciplinary input, but early detection through raising awareness remains key to improving outcomes. In the second article of a two-part series, Manoj Parulekar discusses retinoblastoma management, screening and research. This article has been published in two...

100 years of insulin

3 October 2022 | | Ophthalmology
*Joint first authors The centenary of the discovery of insulin is a time to celebrate one of the most significant scientific discoveries of the 20th century. Background Before 1923, Type 1 diabetes mellitus [T1DM] resulted in death from severe ketoacidosis...

The happiness coefficient: Pete’s hidden curriculum Part 5

4 December 2023 | | Ophthalmology
Jeremy: Come on, man, shake your booty! Tonight even Paxman’s out, hoovering up lines of crank off Krishnan Guru-Murthy. Tonight’s the big one.Mark: Jeremy, all rational people agree it’s a truth self-evident that it’s impossible to have a good time...

Is it NAION… Now what?

3 April 2024 | | Neuro-Ophthalmology
Case presentation We present the case and discussion of a 46-year-old Caucasian male who complained of immediate reduced vision following complicated neck dissection including a total laryngopharyngectomy, free flap reconstruction for a T4N3 squamous cell carcinoma (SCC) of the left...

Immunoglobulin G4-related ophthalmic disease – what is it? (Part 1)

3 February 2023 | | Ophthalmology
Part 1: Epidemiology, classification, radiology, histopathology and associations (see Part 2 here) In this two-part series, Li Yen Goh reviews IgG4 disease and reminds us of diagnostic challenges faced. Introduction Immunoglobulin G4 (IgG4) disease is a recently recognised idiopathic systemic...

Myopia management

1 December 2022 | | Ophthalmology
With the growing prevalence of myopia at epidemic levels in some countries and increasing number of research publications on myopia control, there is a lot of controversy regarding the management of myopia. As none of them are at present available...

It’s not always GCA

7 December 2020 | | Ophthalmology, Neuro-Ophthalmology
Giant cell arteritis (GCA) is an immune mediated granulomatous inflammatory disease that affects muscular middle or large sized arteries. It is considered as a continuation of polymyalgia rheumatica (PMR) when the severity of the disease has increased. It is the...

Under pressure: a tool to aid the 
non-ophthalmic practitioner in the timely management of acute angle closure

1 April 2017 | | Ophthalmology
Acute angle closure is a true ophthalmic emergency that mandates timely diagnosis and treatment. The priority in initial management is to lower the intraocular pressure in an expeditious matter using medical treatments. The risk of irreversible glaucomatous optic neuropathy is...

It’s Friday, I’m In Love: Pete’s Hidden Curriculum Part 3

3 February 2023 | | Ophthalmology
“When you’re in love, it’s the most glorious two-and-a-half days of your life.” - Richard Lewis [1]. The good news is that we are over the hump now and past the most depressing day of the year, which is known...

My top five: Innovative approaches to dry AMD

2 February 2024 | | AMD
Age-related macular degeneration (AMD) is one of the leading causes of irreversible blindness in the developing world with its prevalence rising alongside age. In societies characterised by ageing populations, it is imperative we explore more effective treatment to alleviate the...

Rare eye diseases: progress continues with authorised orphan medicines and breakthrough technologies

1 October 2018 | | Ophthalmology
An update on the development of orphan medicines, recent regulatory treatment approvals for rare eye conditions and advances in retinal prosthetic technologies for blinding diseases. The prevalence of a rare disease is based usually on a range of estimates and...

Could the sclera be key to glaucoma?

1 December 2017 | | Glaucoma
The glaucomas are a group of conditions characterised by optic neuropathy and associated visual field defects. Of these, chronic open-angle glaucoma (COAG) – diagnosed on the basis of progressive structural changes to the optic nerve head (ONH) and nerve fibre...