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Emerging developments in dry eye

1 August 2017 | | Cornea / External Eye Disease
An estimated 344 million people worldwide suffer from dry eye [1]. This chronic syndrome is characterised by a vicious cycle of tear film hyperosmolarity, tear instability and corneal stress, leading to increased friction, inflammation, ocular surface damage and decreased visual...

The role of inflammation in the pathophysiology of DMO

1 February 2016 | | Retina / Uvea / Vitreous
Diabetic macular oedema (DMO) is a major cause of visual loss in diabetes, with a complex multifactorial pathogenesis. In the UK alone it is estimated that there are nearly 2.5 million diabetic patients aged over 12 years. Approximately 65,000 of...

Genetic profiling for personalised healthcare solutions in AMD – an update

1 August 2015 | | Retina / Uvea / Vitreous
Age-related macular degeneration (AMD) is a multifactorial condition influenced by genetics and lifestyle factors (Table 1). This article outlines several recent advances in AMD genetics, as well as evolving therapeutic concepts and established practical measures for the treatment and /...

Contemporary glaucoma therapy: spoilt for choice

1 April 2014 | | Glaucoma
The goal of glaucoma management is to prevent visual loss and disease progression in the patient’s lifetime through effective lowering of intraocular pressure (IOP), the primary modifiable risk factor in glaucoma. Sustained and consistent IOP reduction is key to halting...

Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease

5 February 2020 | | Ophthalmology, Retina / Uvea / Vitreous
Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...

What's trending Feb/Mar 2020

5 February 2020 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
#gbhockey #samward #sight Great Britain Hockey player Sam Ward, described as one of the “deadliest attackers in world hockey” [1], sustained a sight-threatening injury after being struck in the face by a ball during the Olympic qualifying match against Malaysia...

What's trending Apr/May 2018

1 April 2018 | Ophthalmology, Ocular Pathology and Oncology, Cornea / External Eye Disease
Hello again, it’s snowy outside on this March day in the UK. The news of late has been dominated by Storm Emma / the Beast from the East and the Olympics. So without further ado, I bring you an extended...

Orbital cellulitis - an overview of the diagnosis and management

1 February 2022 | | Ophthalmology, Orbit, Neuro-Ophthalmology, Imaging
Periorbital (preseptal) and orbital cellulitis are infections of the subcutaneous tissues of the eye. They are differentiated by the location of the infection. Periorbital cellulitis refers to infection of the eyelid and subcutaneous tissues anterior to the orbital septum, whereas...

My top five: Emerging alternatives to manage and treat nAMD

3 April 2024 | | AMD
Wet (exudative or neovascular) age-related macular degeneration (AMD) is characterised by choroidal neovascularisation, in which new blood vessels from the choroid invade through Bruch’s membrane. These blood vessels proliferate beneath or through the retinal pigment epithelium (RPE), causing patients to...

A paediatric case of central retinal artery occlusion following antibiotics and decompression surgery for orbital cellulitis

3 October 2022 | | Ophthalmology, Paediatric Ophthalmology / Strabismus
Orbital cellulitis is an ophthalmic emergency that warrants urgent management in the hospital setting [1]. This occurs more frequently in the paediatric population where it is often secondary to sinus infections. Delay in treatment could result in severe complications including...

“Steel True, Blade Straight”

1 October 2019 | | Ophthalmology
Steven Kerr of the Royal College of Surgeons of Edinburgh explores the medical career of Arthur Conan Doyle, his relationship with his mentor Joseph Bell and his fascination with ophthalmology. Arthur Ignatius Conan Doyle was born in Edinburgh on the...

Simulating the visual impairment symptoms of age-related macular degeneration in virtual reality

5 June 2023 | | AMD
A new virtual reality application visually simulates age-related macular degeneration and demonstrates its progression over time including some Charles Bonnet syndrome hallucinations. Introduction Age-related macular degeneration (AMD) is the leading cause of blindness in developed countries with the prevalence of...