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Germline testing for uveal melanoma
The authors present a study of 114 consecutive patients presenting with uveal melanoma. Between 1 December 2019 and 1 November 2021 all patients over 18-years-old presenting to their centre with uveal melanoma were offered germline testing for variants in BAP1,...
Retinoblastoma mortality associations with choroidal and optic nerve invasion
The authors present a retrospective cohort study. Data was extracted from the National Cancer Institute’s Surveillance Epidemiology and End Results (SEER) database, based in the US and founded in 1973. Cases of retinoblastoma were extracted using the inclusion criteria of...
A phase 3 randomised trial of nicotinamide for skin cancer chemoprevention
To B3, or not to B3? That was the question asked in this controlled trial in which the authors were able to show that oral nicotinamide (vitamin B3) is able to reduce further skin cancer development in high risk patients....
Ovarian hormones drive onset of Sjogren’s disease in mice
Sjogren’s syndrome (SS) is a debilitating, sight-threatening, systemic autoimmune disease with no effective treatment available. SS is characterised by lacrimal gland lymphocytic infiltration and epithelial cell death, as well as by the presence of serum autoantibodies. Patients have severe dry...
Ten-year experience with intracameral chemotherapy for aqueous seeding in retinoblastoma: long-term efficacy, safety and toxicity
This is a retrospective review of all consecutive patients with primary (n=4) or secondary non-iatrogenic (n=16) aqueous seeding (AS) treated by intracameral chemotherapy (ICC) in Lausanne between 2011 and 2020 with a minimum follow-up of one year. Aqueous seeding control...Jun/Jul 2018 Quiz
History A 35-year-old woman had a long-standing left blind eye following extensive exudative retinal detachment in the past. She later developed increasing pain in her blind eye. Her medical history includes pheochromocytoma resected five years ago, and she is currently...Neuro-ophthalmology: the extended role of an orthoptist
Neuro-ophthalmology has always been a speciality of interest during my studies and now in my career. In 2018, I started a Band 7 post which gave me an extended role in neuro-ophthalmology and the responsibility of developing an orthoptic led...Happy hour
Welcome Eye News Aug/Sep 2023, your bi-monthly tonic for a much-needed happy hour. In the current climate of challenge across all fronts, there’s no better time to reach out for the professional equivalent of a cheery cup in the company...What's trending Apr/May 2018
Hello again, it’s snowy outside on this March day in the UK. The news of late has been dominated by Storm Emma / the Beast from the East and the Olympics. So without further ado, I bring you an extended...Pathophysiology of diabetic macular oedema: why combination therapy may be better
The prevalence of diabetes has continued to increase over the years. It is currently estimated that there are 382 million with diabetes worldwide in 2013, and that this figure is expected to rise to 592 million by 2035 [1]. In...
Ophthalmology
The textbook is a large, single volume that ideally needs to be desk or table-supported, as its sheer weight makes it virtually impossible to rest comfortably on ones lap. The book is compiled by its two lead authors and editors...
