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Bioengineered human tissue
This is a literature review of the current status of tissue engineering related to ocular and oculoplastic reconstructive surgery. The authors describe the process of bioengineering for tissue reconstruction. The aim is to reproduce functional tissue by the use of...
The inflammatory side-effect of Brimonidine
Brimonidine is a well established selective alpha-2 adreno-receptor agonist, used to lower intraocular pressure. This case series reports on 19 eyes affected by brimonidine induced uveitis. Mean age of the patients was 74 years and mean duration of brimonidine use...
New mouse model of diabetes mellitus
Diabetic retinopathy (DR) is a serious complication of diabetes. It is driven by the loss of pericytes, cells which control vascular function, due to excess formation of sugar alcohols by the enzyme aldose reductase (AR). AR has been shown to...
Practice patterns of uveal melanoma management with Iodine-125 brachytherapy
With the 2006 Collaborative Ocular Melanoma Study Group (COMS) study demonstrating no difference in survival outcomes for participants randomised to either iodine-125 brachytherapy or enucleation, the majority of primary uveal melanomas in the United States are now treated with brachytherapy....A revolution in modern genetic testing for the clinical management of ocular disease
Recent years have seen a huge increase in our understanding of the genetic factors underlying a wide variety of eye diseases. This has included common conditions such as glaucoma and age-related macular degeneration, as well as those conditions which have...Glaucoma UK reveals new name, website and branding
Glaucoma UK - formerly the International Glaucoma Association - is using this year’s Glaucoma Awareness Week (GAW) to launch a new name, visual identity and website for the charity, with the aim of reaching more people who have glaucoma, or who are at risk of glaucoma.
Congenital monocular strabismus fixus
The authors describe three cases of congenital monocular strabismus fixus with limited ocular motility in all directions. These were three boys aged two, two and 10 years. The right eye was affected in all with primary deviation angles of 30PD...
Exotropic Moebius syndrome
Three patients are described with pattern C Moebius syndrome and report the technique and outcomes of surgery for two patients. The three cases included a three and a 13-year-old requiring surgery and a 10-year-old. All patients had absent horizontal gaze...
Gradenigo syndrome
The authors report four cases of Gradenigo syndrome (GS) with patients aged five to 70 years; three with classic acute presentation and one with presentation of chronic suppurative otitis media, cholesteatoma and sixth nerve palsy. The authors discuss anatomy, neuroimaging,...
Strabismus in high myopia
The authors report the occurrence of exotropia-hypotropia complex in 15 cases of high myopia. The mean age at presentation was 23.5 years (10-35 years). Only two patients had high bilateral myopia. The mean axial length of the deviating eye was...
Secondary intraocular lens implantation in children
This is a retrospective study of the medical records of children under the age of 16 who underwent secondary lens implantation for aphakic corrections after previous congenital cataract surgery over a period between January 2000 and December 2010. The study...
